2004
Reports: Insulin-Like Growth Factor-I, Soy Protein Intake, and Breast Cancer Risk
Sanderson M, Shu X, Yu H, Dai Q, Malin A, Gao Y, Zheng W. Reports: Insulin-Like Growth Factor-I, Soy Protein Intake, and Breast Cancer Risk. Nutrition And Cancer 2004, 50: 8-15. PMID: 15572292, DOI: 10.1207/s15327914nc5001_2.Peer-Reviewed Original ResearchConceptsIGF-I levelsShanghai Breast Cancer StudyIGFBP-3 levelsSoy protein intakeBreast cancer riskCancer riskProtein intakeBreast cancerInsulin-like growth factor-binding protein-3 levelsPopulation-based case-control studyIncident breast cancer casesPremenopausal breast cancer riskPopulation-based cancer registriesBreast cancer cell growthInsulin-like growth factorPremenopausal breast cancerProtein-3 levelsEffects of IGFCase-control studyBreast cancer casesInsulin-like growthCancer cell growthBreast Cancer StudyPostmenopausal womenCancer Registry
1998
Insulin‐like growth factor–binding protein‐3 and breast cancer survival
Yu H, Levesque M, Khosravi M, Papanastasiou‐Diamandi A, Clark G, Diamandis E. Insulin‐like growth factor–binding protein‐3 and breast cancer survival. International Journal Of Cancer 1998, 79: 624-628. PMID: 9842972, DOI: 10.1002/(sici)1097-0215(19981218)79:6<624::aid-ijc12>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorActions of IGFsIGFBP-3IGF-binding proteinsBreast cancer recurrenceS-phase fractionTumor sizeCancer recurrenceBreast cancerInsulin-like growth factor-binding protein-3Elevated S-phase fractionHigher IGFBP-3 levelsInhibits breast cancer cell growthBreast cancer cell growthDiagnosis-matched patientsIGFBP-3 levelsUnfavourable prognostic featuresUnfavourable prognostic indicatorPrimary breast cancerEstrogen receptor expressionLarger tumor sizeRisk of deathBreast cancer survivalCase-control studyBreast tissue extracts