The insulin-like growth factor axis and risk of liver disease in hepatitis C virus/HIV-co-infected women
Strickler H, Howard A, Peters M, Fazzari M, Yu H, Augenbraun M, French A, Young M, Gange S, Anastos K, Kovacs A. The insulin-like growth factor axis and risk of liver disease in hepatitis C virus/HIV-co-infected women. AIDS 2008, 22: 527-531. PMID: 18301066, PMCID: PMC3507535, DOI: 10.1097/qad.0b013e3282f22cdf.Peer-Reviewed Original ResearchConceptsHIV-positive subjectsHIV-positive womenHepatic stellate cellsIGFBP-3Liver diseaseAPRI levelsLiver fibrosisInsulin-like growth factor binding protein 3Insulin-like growth factor (IGF) axisGrowth factor binding protein 3CD4 T-cell countWomen's Interagency HIV StudyLarge multi-institutional cohortInsulin-like growth factor IBaseline serum specimensHigher IGFBP-3T-cell countsHigh-risk patientsMulti-institutional cohortGrowth factor axisHepatitis C virusLiver function test dataGrowth factor IBinding protein 3Extracellular matrix accumulation