2020
Supervariants identification for breast cancer
Hu J, Li T, Wang S, Zhang H. Supervariants identification for breast cancer. Genetic Epidemiology 2020, 44: 934-947. PMID: 32808324, PMCID: PMC7924970, DOI: 10.1002/gepi.22350.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesCombination of allelesRare variantsNovel lociChromosome 2UK Biobank databaseChromosome 1Multiple lociAssociation studiesLociComplex diseasesGenesBiobank databaseAssociation methodGenomeVariantsTens of thousandsAllelesPolymorphismNovel resultsSignalsClassic conceptIdentification
2019
An accurate and powerful method for copy number variation detection
Xiao F, Luo X, Hao N, Niu YS, Xiao X, Cai G, Amos CI, Zhang H. An accurate and powerful method for copy number variation detection. Bioinformatics 2019, 35: 2891-2898. PMID: 30649252, PMCID: PMC6735918, DOI: 10.1093/bioinformatics/bty1041.Peer-Reviewed Original Research
2013
NCK2 Is Significantly Associated with Opiates Addiction in African‐Origin Men
Liu Z, Guo X, Jiang Y, Zhang H. NCK2 Is Significantly Associated with Opiates Addiction in African‐Origin Men. The Scientific World JOURNAL 2013, 2013: 748979. PMID: 23533358, PMCID: PMC3603435, DOI: 10.1155/2013/748979.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsNCK2 geneGenome-wide significant associationGenome-wide significant levelWide association studyGene-based methodsNumerous genetic variantsGWAS discoveryChromosome 2Association studiesNck2Genetic variantsGenesNucleotide polymorphismsComplex diseasesFirst evidenceGenetic disordersDiscoverySignificant levelsPolymorphismVariantsSubstantial effort
2006
Family‐based association tests for ordinal traits adjusting for covariates
Wang X, Ye Y, Zhang H. Family‐based association tests for ordinal traits adjusting for covariates. Genetic Epidemiology 2006, 30: 728-736. PMID: 17086513, DOI: 10.1002/gepi.20184.Peer-Reviewed Original Research
2002
Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome
Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome. American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.Peer-Reviewed Original ResearchAllelesBehavioral SymptomsChromosomes, HumanChromosomes, Human, Pair 17Chromosomes, Human, Pair 4Chromosomes, Human, Pair 5Gene FrequencyGenetic LinkageGenetic MarkersGenome, HumanHumansMatched-Pair AnalysisNuclear FamilyObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableSoftwareStatistics, NonparametricTourette Syndrome
2000
Use of classification trees for association studies
Zhang H, Bonney G. Use of classification trees for association studies. Genetic Epidemiology 2000, 19: 323-332. PMID: 11108642, DOI: 10.1002/1098-2272(200012)19:4<323::aid-gepi4>3.0.co;2-5.Peer-Reviewed Original Research
1995
Extreme Discordant Sib Pairs for Mapping Quantitative Trait Loci in Humans
Risch N, Zhang H. Extreme Discordant Sib Pairs for Mapping Quantitative Trait Loci in Humans. Science 1995, 268: 1584-1589. PMID: 7777857, DOI: 10.1126/science.7777857.Peer-Reviewed Original Research