Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS)
Wolff EF, He Y, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, Miller VM, Naftolin F, Pal L, Santoro N, Zhang H, Harman SM, Taylor HS. Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS). Fertility And Sterility 2013, 99: 1385-1391. PMID: 23312232, PMCID: PMC3615128, DOI: 10.1016/j.fertnstert.2012.11.053.Peer-Reviewed Original ResearchMeSH KeywordsAdultCarotid Artery DiseasesCarotid Intima-Media ThicknessCohort StudiesCoronary Artery DiseaseDisease ProgressionDyspareuniaEstrogen Replacement TherapyEstrogensFemaleFollow-Up StudiesHot FlashesHumansLongitudinal StudiesMenopauseMiddle AgedMood DisordersPredictive Value of TestsSelf ReportConceptsKronos Early Estrogen Prevention StudyCarotid intima-media thicknessSelf-reported menopausal symptomsIntima-media thicknessMenopausal symptomsMenopausal womenSubclinical atherosclerosisVaginal drynessPrevention StudyEarly menopausal womenElevated CAC scorePredictors of CACCoronary artery calcificationMeasures of atherosclerosisSerum E2 levelsSymptoms of insomniaSelf-reported symptomsCross-sectional analysisLogistic regression modelsMenopause onsetArtery calcificationCAC scoreNight sweatsPersistent symptomsClimacteric symptoms