2017
Genome‐wide mediation analysis of psychiatric and cognitive traits through imaging phenotypes
Bi X, Yang L, Li T, Wang B, Zhu H, Zhang H. Genome‐wide mediation analysis of psychiatric and cognitive traits through imaging phenotypes. Human Brain Mapping 2017, 38: 4088-4097. PMID: 28544218, PMCID: PMC5568842, DOI: 10.1002/hbm.23650.Peer-Reviewed Original Research
2012
A left cerebellar pathway mediates language in prematurely-born young adults
Constable RT, Vohr BR, Scheinost D, Benjamin JR, Fulbright RK, Lacadie C, Schneider KC, Katz KH, Zhang H, Papademetris X, Ment LR. A left cerebellar pathway mediates language in prematurely-born young adults. NeuroImage 2012, 64: 371-378. PMID: 22982585, PMCID: PMC3508203, DOI: 10.1016/j.neuroimage.2012.09.008.Peer-Reviewed Original ResearchConceptsPT subjectsTerm controlsInferior frontal gyrusFunctional MRIFunctional connectivityResting-state functional MRIYoung adultsCognitive outcomesSeed-based connectivity analysisAge 20 yearsSeed-based analysisAlternative neural pathwaysControl young adultsPreterm subjectsCerebellar connectivityNeural pathwaysCerebellar pathwaysIndex scoreNineteen ptsGray matterMaternal educationQuadrangular lobuleDevelopmental delayPT brainSignificant positive correlation
2011
Sex differences in grey matter atrophy patterns among AD and aMCI patients: Results from ADNI
Skup M, Zhu H, Wang Y, Giovanello KS, Lin JA, Shen D, Shi F, Gao W, Lin W, Fan Y, Zhang H, Initiative T. Sex differences in grey matter atrophy patterns among AD and aMCI patients: Results from ADNI. NeuroImage 2011, 56: 890-906. PMID: 21356315, PMCID: PMC3085726, DOI: 10.1016/j.neuroimage.2011.02.060.Peer-Reviewed Original ResearchConceptsGrey matter atrophy patternsAlzheimer's Disease Neuroimaging InitiativeProbable Alzheimer's diseaseAlzheimer's diseaseAmnestic mild cognitive impairmentAtrophy patternsDisease Neuroimaging InitiativeLongitudinal magnetic resonance imaging (MRI) dataPredetermined brain regionsBilateral caudate nucleusAMCI groupBilateral middle temporal gyrusVoxel-wise analysisMild cognitive impairmentGray matter regionsMiddle temporal gyrusBilateral thalamusBrain atrophyStructural MRI dataHealthy controlsGrey matter dataMagnetic resonance imaging dataAD groupBilateral precuneusCaudate nucleus
2005
Localizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS)
McNally KA, Paige AL, Varghese G, Zhang H, Novotny EJ, Spencer SS, Zubal IG, Blumenfeld H. Localizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS). Epilepsia 2005, 46: 1450-1464. PMID: 16146441, DOI: 10.1111/j.1528-1167.2005.06705.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingElectroencephalographyEpilepsyEpilepsy, Temporal LobeFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMaleMiddle AgedNeocortexPreoperative CareReproducibility of ResultsROC CurveTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonVideotape RecordingConceptsStatistical parametric mappingIctal-interictal SPECTSeizure onsetMultiple brain regionsPostictal SPECTBrain regionsLateralized seizure onsetInterictal scansPostictal scansIctal SPECTDecreased perfusionSeizure endEpilepsy casesMesial temporalPerfusion increaseSPECT analysisSPECT scansSeizuresLocalized epilepsyParametric mappingTracer injectionSPECTInjectionPatientsEpilepsy
1998
A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette Syndrome
Peterson BS, Skudlarski P, Anderson AW, Zhang H, Gatenby JC, Lacadie CM, Leckman JF, Gore JC. A Functional Magnetic Resonance Imaging Study of Tic Suppression in Tourette Syndrome. JAMA Psychiatry 1998, 55: 326-333. PMID: 9554428, DOI: 10.1001/archpsyc.55.4.326.Peer-Reviewed Original ResearchConceptsTic suppressionTourette syndromeTic symptomsBasal gangliaPathogenesis of ticsVoluntary tic suppressionMagnetic resonance imaging studyResonance imaging studyFunctional magnetic resonance imaging studySubcortical neural circuitsFunctional magnetic resonance imagingMagnetic resonance imagingConnected cortical regionsRegional signal changesImpaired modulationSignal changesFunctional debilityNeuronal activityResonance imagingAdult subjectsImaging studiesCortical regionsNeuropsychiatric disordersNeural circuitsSyndrome