2019
An accurate and powerful method for copy number variation detection
Xiao F, Luo X, Hao N, Niu YS, Xiao X, Cai G, Amos CI, Zhang H. An accurate and powerful method for copy number variation detection. Bioinformatics 2019, 35: 2891-2898. PMID: 30649252, PMCID: PMC6735918, DOI: 10.1093/bioinformatics/bty1041.Peer-Reviewed Original Research
2017
modSaRa: a computationally efficient R package for CNV identification
Xiao F, Niu Y, Hao N, Xu Y, Jin Z, Zhang H. modSaRa: a computationally efficient R package for CNV identification. Bioinformatics 2017, 33: 2384-2385. PMID: 28453611, PMCID: PMC5860124, DOI: 10.1093/bioinformatics/btx212.Peer-Reviewed Original ResearchConceptsComputational complexityHigh computational complexityR packageOptimal computational complexityUser-friendly R packageEfficient R packageSupplementary dataCurrent versionComputational algorithmDesirable accuracyComplexityPackageComprehensive toolCNV identificationDownloadAlgorithmVariant identificationBioinformaticsImplementationTypes of variationRCPPAccuracyIntegrationStepTool
2009
Analysis of Twin Data Using SAS
Feng R, Zhou G, Zhang M, Zhang H. Analysis of Twin Data Using SAS. Biometrics 2009, 65: 584-589. PMID: 18647295, PMCID: PMC2700843, DOI: 10.1111/j.1541-0420.2008.01098.x.Peer-Reviewed Original ResearchWillows: a memory efficient tree and forest construction package
Zhang H, Wang M, Chen X. Willows: a memory efficient tree and forest construction package. BMC Bioinformatics 2009, 10: 130. PMID: 19416535, PMCID: PMC2683818, DOI: 10.1186/1471-2105-10-130.Peer-Reviewed Original ResearchMeSH KeywordsComputational BiologyGenome-Wide Association StudyPolymorphism, Single NucleotideSoftwareConceptsMassive genotype dataUser-friendly interfaceExcessive memory demandsHigh-dimensional dataNew software packageGenomic dataFriendly interfaceUse of memoryDimensional dataMassive amountsRandom forestPartitioning techniquesHigh-throughput genomic dataPowerful bioinformatics toolsEfficient treeComputer memorySoftware packageMassive sizeForest methodMemory demandsConstruction packagesSingle nucleotide polymorphismsBioinformatics toolsSNP dataGenotyping platforms
2008
LOT: a tool for linkage analysis of ordinal traits for pedigree data
Zhang M, Feng R, Chen X, Hu B, Zhang H. LOT: a tool for linkage analysis of ordinal traits for pedigree data. Bioinformatics 2008, 24: 1737-1739. PMID: 18535081, PMCID: PMC2566542, DOI: 10.1093/bioinformatics/btn258.Peer-Reviewed Original Research
2002
Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome
Zhang H, Leckman JF, Pauls DL, Tsai CP, Kidd KK, Campos MR, Genetics T. Genomewide Scan of Hoarding in Sib Pairs in Which Both Sibs Have Gilles de la Tourette Syndrome. American Journal Of Human Genetics 2002, 70: 896-904. PMID: 11840360, PMCID: PMC379118, DOI: 10.1086/339520.Peer-Reviewed Original ResearchAllelesBehavioral SymptomsChromosomes, HumanChromosomes, Human, Pair 17Chromosomes, Human, Pair 4Chromosomes, Human, Pair 5Gene FrequencyGenetic LinkageGenetic MarkersGenome, HumanHumansMatched-Pair AnalysisNuclear FamilyObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableSoftwareStatistics, NonparametricTourette Syndrome