2019
Optimal timing of antenatal corticosteroid administration and preterm neonatal and early childhood outcomes
Battarbee AN, Ros ST, Esplin MS, Biggio J, Bukowski R, Parry S, Zhang H, Huang H, Andrews W, Saade G, Sadovsky Y, Reddy UM, Varner MW, Manuck TA, Research E. Optimal timing of antenatal corticosteroid administration and preterm neonatal and early childhood outcomes. American Journal Of Obstetrics & Gynecology MFM 2019, 2: 100077. PMID: 32905377, PMCID: PMC7469940, DOI: 10.1016/j.ajogmf.2019.100077.Peer-Reviewed Original ResearchConceptsRespiratory distress syndromeAntenatal corticosteroid administrationEarly childhood morbidityAntenatal corticosteroidsSevere neonatal morbidityChildhood morbidityDistress syndromeNeonatal morbidityCorticosteroid administrationSteroid administrationPreterm neonatesOptimal timingComposite neonatal morbidityPreterm birth researchCourse of corticosteroidsMean gestational ageSpontaneous preterm birthSpontaneous preterm laborProspective multicenter studyLong-term outcomesMultivariable logistic regressionEarly childhood outcomesAntenatal magnesiumNeonatal outcomesPreterm labor
2010
The Impact of Environmental and Genetic Factors on Neonatal Late-Onset Sepsis
Bizzarro MJ, Jiang Y, Hussain N, Gruen JR, Bhandari V, Zhang H. The Impact of Environmental and Genetic Factors on Neonatal Late-Onset Sepsis. The Journal Of Pediatrics 2010, 158: 234-238.e1. PMID: 20850766, PMCID: PMC3008342, DOI: 10.1016/j.jpeds.2010.07.060.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetBirth WeightBlood-Borne PathogensCohort StudiesConfidence IntervalsCross InfectionEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHospital MortalityHumansInfant, NewbornIntensive Care Units, NeonatalLogistic ModelsMalePrognosisRetrospective StudiesSepsisSurvival RateTime FactorsTwinsTwins, DizygoticTwins, MonozygoticConceptsLate-onset sepsisNewborn intensive care unitIntensive care unitCare unitBirth weightIntensive care unit populationNeonatal late-onset sepsisRetrospective cohort analysisTotal parenteral nutritionRespiratory distress syndromeGenetic factorsLogistic regression analysisMixed-effects logistic regressionNongenetic factorsMixed-effects logistic regression analysisSignificant genetic susceptibilityDistress syndromeParenteral nutritionGestational ageCohort analysisSepsisUnit populationConcordance rateGenetic susceptibilityLogistic regression
2009
Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn
Bhandari V, Zhou G, Bizzarro MJ, Buhimschi C, Hussain N, Gruen JR, Zhang H. Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn. Pediatrics 2009, 123: 669-673. PMID: 19171636, PMCID: PMC3161726, DOI: 10.1542/peds.2008-1117.Peer-Reviewed Original ResearchConceptsPatent ductus arteriosusDuctus arteriosusRespiratory distress syndromeGestational ageDistress syndromePostmenstrual agePremature newbornsGenetic factorsPreterm patent ductus arteriosusCommon congenital heart diseaseWeeks postmenstrual ageWeeks gestational ageCongenital heart diseaseMixed-effects logistic regressionTwin pairsAntenatal steroidsBronchopulmonary dysplasiaPreterm newbornsSignificant morbidityRetrospective studyOxygen supplementationHeart diseaseMonozygotic twin pairsPremature twinsArteriosus
2006
Genetic Susceptibility to Retinopathy of Prematurity
Bizzarro MJ, Hussain N, Jonsson B, Feng R, Ment LR, Gruen JR, Zhang H, Bhandari V. Genetic Susceptibility to Retinopathy of Prematurity. Pediatrics 2006, 118: 1858-1863. PMID: 17079555, DOI: 10.1542/peds.2006-1088.Peer-Reviewed Original ResearchConceptsRetinopathy of prematuritySupplemental oxygen useLogistic regression analysisGestational ageOxygen useGenetic susceptibilityDuration of ventilationRespiratory distress syndromeLength of stayMixed-effects logistic regression analysisStrong genetic predispositionRegression analysisBronchopulmonary dysplasiaDistress syndromePostmenstrual ageRetrospective studyBirth weightPediatric ophthalmologistsPremature twinsPrematurityRetinopathyGenetic predispositionSignificant covariatesDizygotic twin pairsZygosity data