2023
Anti-Müllerian Hormone Level Decline in Patients Undergoing Hysterectomy With and Without Oophorectomy Compared With Natural Menopause
Santoro N, Flyckt R, Davis A, Finkelstein J, Crawford S, Sun F, Derby C, Morrison A, Sluss P, Zhang H. Anti-Müllerian Hormone Level Decline in Patients Undergoing Hysterectomy With and Without Oophorectomy Compared With Natural Menopause. Obstetrics And Gynecology 2023, 141: 331-340. PMID: 36649324, PMCID: PMC9858351, DOI: 10.1097/aog.0000000000005049.Peer-Reviewed Original ResearchConceptsFinal menstrual periodAnti-Müllerian hormone levelsAMH levelsNatural menopauseHormone levelsUndetectable AMH levelsCommunity-based studyOvarian conservationOvarian reserveAMH measurementOvarian failureMenstrual periodSurgery dateHysterectomyLinear mixed modelingMenopauseSurvival analysisPatientsImmediate reductionMixed modelingWomenOvariesSimilar patternRapid declineBSO
2022
Course of Tic Severity in Tourette Syndrome: The First Two Decades
Leckman J, Zhang H, Vitale A, Lahnin F, Lynch K, Bondi C, Kim Y, Peterson B. Course of Tic Severity in Tourette Syndrome: The First Two Decades. 2022, 80-85. DOI: 10.4324/9780203822937-8.Peer-Reviewed Original ResearchYears of ageDecades of lifeTic severityTourette syndromeTS patientsTic onsetClinical evaluationPrevalence studySeverity of ticsInitial clinical evaluationConsistent time courseTime courseHigh rateOnset of pubertyInitial followPatient's coursePrognostic valueYale Child Study CenterBirth-year cohortsPatientsNatural historySyndromeCurve analysisSeverityStudy centersEffect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial
Barnhart K, Hansen K, Stephenson M, Usadi R, Steiner A, Cedars M, Jungheim E, Hoeger K, Krawetz S, Mills B, Alston M, Coutifaris C, Senapati S, Sonalkar S, Diamond M, Wild R, Rosen M, Sammel M, Santoro N, Eisenberg E, Huang H, Zhang H. Effect of an Active vs Expectant Management Strategy on Successful Resolution of Pregnancy Among Patients With a Persisting Pregnancy of Unknown Location: The ACT or NOT Randomized Clinical Trial. Obstetrical & Gynecological Survey 2022, 77: 24-26. DOI: 10.1097/01.ogx.0000805156.32421.70.Peer-Reviewed Original Research
2015
Recruitment strategies in two reproductive medicine network infertility trials
Usadi RS, Diamond MP, Legro RS, Schlaff WD, Hansen KR, Casson P, Christman G, Bates G, Baker V, Seungdamrong A, Rosen MP, Lucidi S, Thomas T, Huang H, Santoro N, Eisenberg E, Zhang H, Alvero R, Network F. Recruitment strategies in two reproductive medicine network infertility trials. Contemporary Clinical Trials 2015, 45: 196-200. PMID: 26386293, PMCID: PMC4766588, DOI: 10.1016/j.cct.2015.09.010.Peer-Reviewed Original ResearchConceptsPPCOS IIMultiple Intrauterine GestationsPolycystic ovary syndromeRecruitment strategiesSuccessful recruitment strategiesInfertility trialsOvarian stimulationIntrauterine gestationOvary syndromeWhite patientsBlack patientsDifferent recruitment strategiesPhysician referralClinical trialsInfertile couplesTrial completionClinical sitesTrialsRecruitment methodsPatientsSimilar ratesPhysiciansWomenParticipantsSuccessful strategy
2014
Letrozole or Clomiphene for Infertility in the Polycystic Ovary Syndrome
Legro RS, Zhang H. Letrozole or Clomiphene for Infertility in the Polycystic Ovary Syndrome. New England Journal Of Medicine 2014, 371: 1462-1464. PMID: 25295506, DOI: 10.1056/nejmc1409550.Peer-Reviewed Original ResearchA novel staging model to classify oesophageal squamous cell carcinoma patients in China
Tan H, Zhang H, Xie J, Chen B, Wen C, Guo X, Zhao Q, Wu Z, Shen J, Wu J, Xu X, Li E, Xu L, Wang X. A novel staging model to classify oesophageal squamous cell carcinoma patients in China. British Journal Of Cancer 2014, 110: 2109-2115. PMID: 24569468, PMCID: PMC3992487, DOI: 10.1038/bjc.2014.101.Peer-Reviewed Original ResearchConceptsESCC patientsClinical variablesStaging systemOesophageal squamous cell carcinoma patientsSurvival analysisSquamous cell carcinoma patientsOesophageal squamous cell carcinomaKaplan-Meier survival analysisCell carcinoma patientsPotential prognostic factorsTNM staging systemSquamous cell carcinomaMetastasis (TNM) staging systemOesophageal carcinomaPrognostic factorsCarcinoma patientsCell carcinomaSame hospitalESCC prognosisPredominant subtypeRisk scoreIndependent cohortPatientsSurvival rateStaging model
2005
Comparison of survival times in a transplant study of hematologic disorders
Fu P, Laughlin MJ, Zhang H. Comparison of survival times in a transplant study of hematologic disorders. Contemporary Clinical Trials 2005, 27: 174-182. PMID: 16326144, DOI: 10.1016/j.cct.2005.10.003.Peer-Reviewed Original ResearchConceptsHuman leucocyte antigenHematologic disordersWilcoxon testUnrelated donor graftsBone marrow transplantationLog-rank testUmbilical cord bloodEvaluation of survivalNeutrophil recoveryDonor graftsOverall survivalMarrow transplantationGraft sourceCancer patientsPatient populationClinical trialsEffective therapyHematologic malignanciesLeucocyte antigenCord bloodLog rankSurvival timePatientsPatient samplesTransplantation studiesLocalizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS)
McNally KA, Paige AL, Varghese G, Zhang H, Novotny EJ, Spencer SS, Zubal IG, Blumenfeld H. Localizing Value of Ictal–Interictal SPECT Analyzed by SPM (ISAS). Epilepsia 2005, 46: 1450-1464. PMID: 16146441, DOI: 10.1111/j.1528-1167.2005.06705.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingElectroencephalographyEpilepsyEpilepsy, Temporal LobeFemaleFunctional LateralityHumansImage Processing, Computer-AssistedMaleMiddle AgedNeocortexPreoperative CareReproducibility of ResultsROC CurveTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonVideotape RecordingConceptsStatistical parametric mappingIctal-interictal SPECTSeizure onsetMultiple brain regionsPostictal SPECTBrain regionsLateralized seizure onsetInterictal scansPostictal scansIctal SPECTDecreased perfusionSeizure endEpilepsy casesMesial temporalPerfusion increaseSPECT analysisSPECT scansSeizuresLocalized epilepsyParametric mappingTracer injectionSPECTInjectionPatientsEpilepsy
2001
Thermal Sensitivity in Tourette Syndrome: Preliminary Report
Scahill L, Lombroso P, Mack G, Van Wattum P, Zhang H, Vitale A, Leckman J. Thermal Sensitivity in Tourette Syndrome: Preliminary Report. Perceptual And Motor Skills 2001, 92: 419-432. PMID: 11361302, DOI: 10.2466/pms.2001.92.2.419.Peer-Reviewed Original ResearchConceptsTourette syndromeSubgroup of patientsAge of onsetAdult male subjectsCurrent ageTic symptomsDopaminergic pathwaysSex distributionCurrent severityMale subjectsMean differenceSyndromeControl periodPreliminary reportSweat rateAgeSymptomsSubjectsOverall courseDegrees COnsetPatientsIllnessSeverityCourse
1998
Course of Tic Severity in Tourette Syndrome: The First Two Decades
Leckman J, Zhang H, Vitale A, Lahnin F, Lynch K, Bondi C, Kim Y, Peterson B. Course of Tic Severity in Tourette Syndrome: The First Two Decades. Pediatrics 1998, 102: 14-19. PMID: 9651407, DOI: 10.1542/peds.102.1.14.Peer-Reviewed Original ResearchConceptsYears of ageTic severityTS patientsTourette syndromeSeverity of ticsInitial clinical evaluationDecades of lifeConsistent time courseOnset of pubertyPatient's coursePrognostic valueTic onsetYale Child Study CenterClinical evaluationBirth-year cohortsPrevalence studyPatientsSeverityStudy centersChild Study CenterIdentification of factorsSevere levelsAgeProgressive patternSyndrome