Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn
Bhandari V, Zhou G, Bizzarro MJ, Buhimschi C, Hussain N, Gruen JR, Zhang H. Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn. Pediatrics 2009, 123: 669-673. PMID: 19171636, PMCID: PMC3161726, DOI: 10.1542/peds.2008-1117.Peer-Reviewed Original ResearchConceptsPatent ductus arteriosusDuctus arteriosusRespiratory distress syndromeGestational ageDistress syndromePostmenstrual agePremature newbornsGenetic factorsPreterm patent ductus arteriosusCommon congenital heart diseaseWeeks postmenstrual ageWeeks gestational ageCongenital heart diseaseMixed-effects logistic regressionTwin pairsAntenatal steroidsBronchopulmonary dysplasiaPreterm newbornsSignificant morbidityRetrospective studyOxygen supplementationHeart diseaseMonozygotic twin pairsPremature twinsArteriosus