2006
Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies
Zhang H, Wang X, Ye Y. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies. Genetics 2006, 172: 693-699. PMID: 16219774, PMCID: PMC1456175, DOI: 10.1534/genetics.105.049122.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsQuantitative traitsOrdinal traitsTraditional linkage studiesGenomewide association analysisAssociation of genesDetection of genesGametic disequilibriumLoci existAssociation studiesAssociation analysisGenesLinkage disequilibriumTraitsComplex diseasesLinkage studiesGrowth-associated protein 43Protein 43DisequilibriumPolymorphismFamilyMarkersNuclear families
2005
Linkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data
Zhong X, Zhang H. Linkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data. BMC Genomic Data 2005, 6: s31. PMID: 16451641, PMCID: PMC1866754, DOI: 10.1186/1471-2156-6-s1-s31.Peer-Reviewed Original ResearchConceptsLinkage analysisAssociation analysisSusceptibility genesGenetic Analysis Workshop 14Alcoholism dataCombination of linkageComplex disease mappingDisease susceptibility genesEntire genomeMean identityLinkage disequilibriumTransmission/disequilibrium testAssociation TestGenesPresence of linkageDisequilibrium testGenomeChromosomesGeneticsLinkageDisequilibriumAssociation strategyGreater numberRegion