2009
The familial aggregation of cannabis use disorders
Merikangas KR, Li JJ, Stipelman B, Yu K, Fucito L, Swendsen J, Zhang H. The familial aggregation of cannabis use disorders. Addiction 2009, 104: 622-629. PMID: 19335660, PMCID: PMC2794246, DOI: 10.1111/j.1360-0443.2008.02468.x.Peer-Reviewed Original ResearchConceptsSpouses of probandsFirst-degree relativesCannabis use disorderLife-time historyUse disordersAnxiety disordersAlcohol abuse/dependenceFamilial aggregationAbuse/dependenceFirst-degree adult relativesComorbid moodElevated riskFamily-based approachPsychiatric clinicAffective disordersAlcohol dependencePsychiatric conditionsFamily study methodDrug abuseFamilial factorsDisordersAdult relativesCannabisFamilial transmissionGenetic factors
1998
Familial Transmission of Substance Use Disorders
Merikangas KR, Stolar M, Stevens DE, Goulet J, Preisig MA, Fenton B, Zhang H, O'Malley SS, Rounsaville BJ. Familial Transmission of Substance Use Disorders. JAMA Psychiatry 1998, 55: 973-979. PMID: 9819065, DOI: 10.1001/archpsyc.55.11.973.Peer-Reviewed Original ResearchConceptsSubstance use disordersAdult first-degree relativesFirst-degree relativesDrug disordersRisk factorsUse disordersPredominant drugFamilial aggregationPotent risk factorRelatives of probandsAntisocial personality disorderFamily history interviewSubstance disordersFamily historyControl probandsDiagnostic InterviewOpioidsPersonality disorderDisordersFamilial transmissionGenetic factorsProbandsCocaineDrugsCannabis