2003
Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment
SUKHODOLSKY DG, SCAHILL L, ZHANG H, PETERSON BS, KING RA, LOMBROSO PJ, KATSOVICH L, FINDLEY D, LECKMAN JF. Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment. Journal Of The American Academy Of Child & Adolescent Psychiatry 2003, 42: 98-105. PMID: 12500082, DOI: 10.1097/00004583-200301000-00016.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderComorbid attention-deficit/hyperactivity disorderDisruptive behaviorFamily functioningParent ratingsTeacher ratingsDiagnosis of ADHDVineland Adaptive Behavior ScalesDisruptive behavior problemsHierarchical regression analysisAdaptive Behavior ScalesBest-estimate DSM-IV diagnosesUnaffected control childrenTourette syndromeConduct problemsDelinquency scoresHyperactivity disorderADHD comorbidityDelinquent behaviorBehavior problemsDSM-IV diagnosisDependent measuresDiagnostic statusBehavior ScaleFunctional impairment
2000
Preliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity Disorders
Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P. Preliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity Disorders. JAMA Psychiatry 2000, 57: 364-372. PMID: 10768698, DOI: 10.1001/archpsyc.57.4.364.Peer-Reviewed Original ResearchConceptsBasal ganglia volumesAttention-deficit/hyperactivity disorderAntistreptococcal antibody titersObsessive-compulsive disorderAntibody titersGanglia volumesStreptococcal infectionAntistreptococcal antibodiesPreliminary serological evidencePrior streptococcal infectionRecurrent streptococcal infectionsHyperactivity disorderPresence of ADHDBasal ganglia nucleiHigh antibody titersGlobus pallidus nucleusDSM-IV diagnosisStreptococcal exposurePallidus nucleusAntistreptolysin OOCD comorbiditySerological evidenceSusceptible personsTic disordersDiagnostic comorbidity