2018
Optimal treatment for women with a persisting pregnancy of unknown location, a randomized controlled trial: The ACT-or-NOT trial
Barnhart KT, Sammel MD, Stephenson M, Robins J, Hansen KR, Youssef WA, Santoro N, Eisenberg E, Zhang H, Network F. Optimal treatment for women with a persisting pregnancy of unknown location, a randomized controlled trial: The ACT-or-NOT trial. Contemporary Clinical Trials 2018, 73: 145-151. PMID: 30243810, PMCID: PMC6231403, DOI: 10.1016/j.cct.2018.09.009.Peer-Reviewed Original ResearchConceptsOutcome measuresHuman chorionic gonadotropin concentrationRuptured ectopic pregnancyPositive pregnancy testSecondary outcome measuresExtra-uterine pregnancyInitial management strategyPrimary outcome measureChorionic gonadotropin concentrationsPatient satisfaction outcomesInitial management planAcademic medical centerEvidence-based managementAdditional ultrasonographyPersistent PULEctopic pregnancyExpectant managementAdverse eventsClinical resolutionEmpiric useGonadotropin concentrationsTransvaginal ultrasonographyTreatment complicationsTreatment armsUterine evacuationEvaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation
Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H, Network F. Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation. Contemporary Clinical Trials 2018, 68: 1-6. PMID: 29524590, PMCID: PMC5899676, DOI: 10.1016/j.cct.2018.03.002.Peer-Reviewed Original ResearchConceptsReproductive Medicine NetworkDisease-specific questionnaireReproductive-aged womenTime of surgeryEstrogen-dependent conditionStage of endometriosisExtensive clinical evaluationSeverity of diseaseNoninvasive diagnostic biomarkersAcademic medical centerPelvic painEndometrial biopsyNonsurgical diagnosisSerum cytokinesSurgical ablationGynecologic surgeryClinical evaluationClinical reasonsMedical CenterAged womenPharmacological controlEndometriosisGenomic classifierSpecific questionnaireTherapy shifts
2015
Predictors of participant retention in infertility treatment trials
Kuang H, Jin S, Thomas T, Engmann L, Hansen KR, Coutifaris C, Casson P, Christman G, Alvero R, Santoro N, Eisenberg E, Diamond MP, Legro RS, Zhang H, Network R, Bartlebaugh C, Dodson W, Estes S, Gnatuk C, Ladda R, Ober J, Easton C, Hernandez A, Leija M, Pierce D, Bryzski R, Awonuga A, Cedo L, Cline A, Collins K, Krawetz S, Puscheck E, Singh M, Yoscovits M, Barnhart K, Lecks K, Martino L, Marunich R, Snyder P, Schlaff W, Comfort A, Crow M, Hohmann A, Mallette S, Ringbloom M, Tang J, Mason S, DiMaria N, Rhea M, Turner K, Haisenleder D, Trussell J, DelBasso D, Li Y, Makuch R, Patrizio P, Sakai L, Scahill L, Taylor H, Thomas T, Tsang S, Zhang M, Lamar C, DePaolo L, Guzick D, Herring A, Redmond J, Thomas M, Turek P, Wactawski-Wende J, Rebar R, Cato P, Dukic V, Lewis V, Schlegel P, Witter F. Predictors of participant retention in infertility treatment trials. Fertility And Sterility 2015, 104: 1236-1243.e2. PMID: 26354094, PMCID: PMC4630082, DOI: 10.1016/j.fertnstert.2015.08.001.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdolescentAdultChi-Square DistributionDrug Therapy, CombinationFemaleFertilityFertility Agents, FemaleHumansInfertility, FemaleLogistic ModelsMaleMultivariate AnalysisOdds RatioPatient DropoutsPatient SelectionPolycystic Ovary SyndromePregnancyRandomized Controlled Trials as TopicRisk FactorsTreatment OutcomeYoung AdultConceptsPolycystic ovary syndromeBody mass indexClomiphene citrateClinical trialsHistory of smokingInsurance coverageCombination of metforminMultivariable logistic modelAcademic medical centerRetention of subjectsConduct of RCTsBetter insurance coverageUnexplained infertilityOvary syndromeNormal weightMass indexOriginal RCTTreatment trialsMedical CenterMAIN OUTCOMEWhite raceIntervention studiesRCTsSecondary analysisParticipant retention
2012
Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility
Huang H, Hansen KR, Factor-Litvak P, Carson SA, Guzick DS, Santoro N, Diamond MP, Eisenberg E, Zhang H, Network I. Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility. Fertility And Sterility 2012, 97: 959-967.e5. PMID: 22270557, PMCID: PMC3319287, DOI: 10.1016/j.fertnstert.2012.01.090.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAlcohol DrinkingAlcoholic BeveragesChi-Square DistributionCoffeeFemaleHumansInfertilityInfertility, MaleInsemination, ArtificialLife StyleLive BirthLogistic ModelsMaleMiddle AgedMultivariate AnalysisOvulation InductionPregnancyPregnancy RateProspective StudiesRisk AssessmentRisk FactorsRisk Reduction BehaviorSuperovulationSurveys and QuestionnairesTeaTreatment OutcomeUnited StatesYoung AdultConceptsLive birth rateMale factor infertilityLive birthsPregnancy outcomesHigher pregnancyBirth ratePredictors of pregnancyAlcoholic beveragesFemale partnersOccurrence of pregnancyAcademic medical centerLifestyle factorsIntrauterine inseminationRisk factorsLifestyle questionnaireOccupational exposureMedical CenterLifestyle changesMAIN OUTCOMETreatment groupsPregnancySecondary analysisPast usersCurrent usersBirth