Positron emission tomography study of pindolol occupancy of 5-HT1A receptors in humans: preliminary analyses
Martinez D, Mawlawi O, Hwang D, Kent J, Simpson N, Parsey R, Hashimoto T, Slifstein M, Huang Y, Van Heertum R, Abi-Dargham A, Caltabiano S, Malizia A, Cowley H, Mann J, Laruelle M. Positron emission tomography study of pindolol occupancy of 5-HT1A receptors in humans: preliminary analyses. Nuclear Medicine And Biology 2000, 27: 523-527. PMID: 10962261, DOI: 10.1016/s0969-8051(00)00122-0.Peer-Reviewed Original ResearchConceptsDorsal raphe nucleusClinical studiesPositron emission tomographyPlacebo-controlled clinical studySerotonin reuptake inhibitor therapyCortical regionsAbility of pindololPositron emission tomography studyInitiation of treatmentEmission tomography studiesDRN 5Pindolol augmentationPindolol doseAntidepressant therapyAntidepressant responseInhibitor therapySerotonin transmissionRaphe nucleusScan 3SSRI effectsPostsynaptic receptorsScan 4Clinical trialsOral administrationPreclinical studies