2020
Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing
Gorecka J, Gao X, Fereydooni A, Dash BC, Luo J, Lee SR, Taniguchi R, Hsia HC, Qyang Y, Dardik A. Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing. Regenerative Medicine 2020, 15: 1277-1293. PMID: 32228292, PMCID: PMC7304438, DOI: 10.2217/rme-2019-0086.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiabetes Mellitus, ExperimentalDiabetic FootHumansInduced Pluripotent Stem CellsMaleMesenchymal Stem CellsMiceMice, NudeMyocytes, Smooth MuscleNeovascularization, PhysiologicWound HealingConceptsSmooth muscle cellsMuscle cellsDiabetic wound healingWound healingPro-angiogenic cytokinesMurine AdiposeStem cellsType macrophagesCollagen scaffoldsCultured mediumM2-type macrophagesCellsNumber of totalNew candidatesAngiogenesisNude miceDiabetic woundsPromising new candidateScaffoldsHealingCytokinesExpressionSecreteWoundsAdipose
2019
Incisional Negative Pressure Wound Therapy Augments Perfusion and Improves Wound Healing in a Swine Model Pilot Study.
Shah A, Sumpio BJ, Tsay C, Swallow M, Dash B, Thorn SL, Sinusas AJ, Koo A, Hsia HC, Au A. Incisional Negative Pressure Wound Therapy Augments Perfusion and Improves Wound Healing in a Swine Model Pilot Study. Annals Of Plastic Surgery 2019, 82: s222-s227. PMID: 30855392, DOI: 10.1097/sap.0000000000001842.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsMaleModels, AnimalNegative-Pressure Wound TherapyNeovascularization, PhysiologicPilot ProjectsRegional Blood FlowSwineWound HealingConceptsNegative pressure wound therapyVascular endothelial growth factorClosed woundsUse of NPWTVEGF expressionSurgical wound sitePressure wound therapyMale Yorkshire pigsEnzyme-linked immunosorbent assay resultsEnzyme-linked immunosorbent assayEndothelial growth factorExcisional wound modelImmunosorbent assay resultsControl dressingsPrimary sutureScar evaluationImmunohistochemistry stainingIncision siteNPWT dressingsWound therapyAngiogenesis markersTreatment groupsAppearance of woundsOpen woundsWound healing model