1986
Effect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis.
Sandle G, Hayslett J, Binder H. Effect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis. Gut 1986, 27: 309. PMID: 3699552, PMCID: PMC1433405, DOI: 10.1136/gut.27.3.309.Peer-Reviewed Original ResearchConceptsActive ulcerative colitisInactive ulcerative colitisUlcerative colitisControl subjectsPharmacological dosesIntravenous administrationNet sodiumAcute ulcerative colitisAnti-inflammatory actionEffects of glucocorticoidsNet sodium absorptionColonic sodiumRectal pdAcute increaseAcute effectsColitisHydrocortisone hemisuccinateNormal subjectsPatientsGlucocorticoid hormonesSodium absorptionNet electrolyteGlucocorticoidsSimilar increaseSimilar changes
1975
A Controlled Evaluation of Intravenous Adrenocorticotropic Hormone and Hydrocortisone in the Treatment of Acute Colitis
Kaplan H, Portnoy B, Binder H, Amatruda T, Spiko H. A Controlled Evaluation of Intravenous Adrenocorticotropic Hormone and Hydrocortisone in the Treatment of Acute Colitis. Gastroenterology 1975, 69: 91-95. PMID: 168121, DOI: 10.1016/s0016-5085(19)32640-x.Peer-Reviewed Original ResearchConceptsIntravenous adrenocorticotropic hormoneAdrenocorticotropic hormoneSymptomatic inflammatory bowel diseaseSystemic steroid levelsInflammatory bowel diseaseDouble-blind techniqueTreatment of patientsConsecutive hospital patientsPlasma cortisol levelsIntravenous hydrocortisoneTherapeutic lagAcute colitisBowel diseasePatient evaluationHospital patientsDrug dosesControlled EvaluationEquivalent dosageSteroid levelsCortisol levelsExcretion rateDrug selectionHydrocortisonePatientsBlind technique