Evaluation of Oral Rehydration Solution by Whole‐Gut Perfusion in Rats: Effect of Osmolarity, Sodium Concentration and Resistant Starch
Subramanya S, Ramakrishna BS, Binder HJ, Farthing MJ, Young GP. Evaluation of Oral Rehydration Solution by Whole‐Gut Perfusion in Rats: Effect of Osmolarity, Sodium Concentration and Resistant Starch. Journal Of Pediatric Gastroenterology And Nutrition 2006, 43: 568-575. PMID: 17130730, DOI: 10.1097/01.mpg.0000239998.43141.b2.Peer-Reviewed Original ResearchConceptsOsmolarity oral rehydration solutionGlucose-ORSOral rehydration solutionNet water absorptionRehydration solutionWhole-gut perfusionSmall bowel absorptionColonic fluid absorptionSeverity of diarrheaAmylase-resistant starchSteady-state perfusionEscherichia coli heat-stable enterotoxinColi heat-stable enterotoxinBowel perfusionBowel absorptionSevere diarrheaDifferent etiologiesHigher net absorptionSegmental perfusionWistar ratsHeat-stable enterotoxinClinical practiceNet secretionExperimental animalsPerfusion