Evaluation of Oral Rehydration Solution by Whole‐Gut Perfusion in Rats: Effect of Osmolarity, Sodium Concentration and Resistant Starch
Subramanya S, Ramakrishna BS, Binder HJ, Farthing MJ, Young GP. Evaluation of Oral Rehydration Solution by Whole‐Gut Perfusion in Rats: Effect of Osmolarity, Sodium Concentration and Resistant Starch. Journal Of Pediatric Gastroenterology And Nutrition 2006, 43: 568-575. PMID: 17130730, DOI: 10.1097/01.mpg.0000239998.43141.b2.Peer-Reviewed Original ResearchConceptsOsmolarity oral rehydration solutionGlucose-ORSOral rehydration solutionNet water absorptionRehydration solutionWhole-gut perfusionSmall bowel absorptionColonic fluid absorptionSeverity of diarrheaAmylase-resistant starchSteady-state perfusionEscherichia coli heat-stable enterotoxinColi heat-stable enterotoxinBowel perfusionBowel absorptionSevere diarrheaDifferent etiologiesHigher net absorptionSegmental perfusionWistar ratsHeat-stable enterotoxinClinical practiceNet secretionExperimental animalsPerfusionAmylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea
Raghupathy P, Ramakrishna BS, Oommen SP, Ahmed MS, Priyaa G, Dziura J, Young GP, Binder HJ. Amylase‐Resistant Starch as Adjunct to Oral Rehydration Therapy in Children with Diarrhea. Journal Of Pediatric Gastroenterology And Nutrition 2006, 42: 362-368. PMID: 16641573, DOI: 10.1097/01.mpg.0000214163.83316.41.Peer-Reviewed Original ResearchConceptsOral rehydration solutionAmylase-resistant starchGlucose-ORSDuration of diarrheaStool weightAcute diarrheaStandard treatmentFluid absorptionG-ORS groupMean stool weightIntravenous fluid therapyAcute watery diarrheaOral rehydration therapySeverity of diarrheaTreatment of diarrheaShort-chain fatty acidsColonic sodiumEvaluable dataRehydration therapyTreatment failureFluid therapyWatery diarrheaRehydration solutionIntestinal sodiumDiarrhea