2004
Three distinct mechanisms of HCO3− secretion in rat distal colon
Vidyasagar S, Rajendran VM, Binder HJ. Three distinct mechanisms of HCO3− secretion in rat distal colon. American Journal Of Physiology - Cell Physiology 2004, 287: c612-c621. PMID: 15308466, DOI: 10.1152/ajpcell.00474.2003.Peer-Reviewed Original ResearchConceptsRat distal colonShort-chain fatty acidsColonic mucosaDistal colonRat distal colonic mucosaDistal colonic mucosaCl- channel blockerSCFA/Channel blockersSerosal layerCrypt cellsCFTR blockerMicroM DIDSApical membrane anion channelApical membraneSecretionDependent secretionColonLumen ClSecretory mechanismMammalian colonBlockersMucosaStat techniqueDIDS
2003
Na-H Exchange Function in Colonic Epithelial Cells
Binder H, Rajendran V, Geibel J. Na-H Exchange Function in Colonic Epithelial Cells. 2003, 71-90. DOI: 10.1007/978-1-4615-0427-6_5.Peer-Reviewed Original ResearchColonic epithelial cellsShort-chain fatty acidsEpithelial cellsSmall intestinal epithelial cellsAbsorption of carbohydratesIntestinal epithelial cellsSecretion of fluidEpithelial cell functionNeonatal periodCrypt cellsDistal segmentsCell functionSignificant heterogeneityMammalian colonSecretory processColonFatty acidsCl transportMultiple factorsCellsNutrient absorptionExchange functionHormoneSecretion
2002
HKcαEncodes Ouabain-insensitive H,K-ATPase in Surface Cells of Rat Distal Colon
Binder H. HKcαEncodes Ouabain-insensitive H,K-ATPase in Surface Cells of Rat Distal Colon. 2002, 43-52. DOI: 10.1007/978-1-4615-0971-4_4.Peer-Reviewed Original ResearchRenal functionK secretionActive K secretionNormal renal functionReduced renal functionActive K absorptionDietary K intakeNormal dietary intakeRat distal colonNet K secretionMammalian colonK-ATPaseK homeostasisActive transport mechanismK intakeDistal colonDietary intakeExperimental animalsLarge intestineK absorptionTransport mechanismColonSecretionImportant siteNormal conditions
2001
Na+-dependent fluid absorption in intact perfused rat colonic crypts
Geibel J, Rajendran V, Binder H. Na+-dependent fluid absorption in intact perfused rat colonic crypts. Gastroenterology 2001, 120: 144-150. PMID: 11208723, DOI: 10.1053/gast.2001.20890.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAnimalsBicarbonatesChloridesColonGanglionic StimulantsGlutamatesIn Vitro TechniquesIntestinal AbsorptionInulinIsotonic SolutionsMalePerfusionQuaternary Ammonium CompoundsRatsRats, Sprague-DawleyRinger's SolutionSodiumSodium-Hydrogen ExchangersTritiumConceptsNet fluid absorptionRat colonic cryptsCl- channel blockerFluid absorptionNeurohumoral stimulationChannel blockersColonic cryptsLumen ClAbsorptive processesInhibitor of NaCl(-) secretionAbstractTextCrypt cellsExchange inhibitorMicroperfusion techniqueFluid secretionL DIDSAmiloride analoguesMammalian colonSecretionAnion exchange inhibitorCryptsSignificant increaseAIMSSecretory process
1987
Chapter 21 Potassium Adataptation in Mammalian Colon
Hayslett J, Binder H, Kashgarian M. Chapter 21 Potassium Adataptation in Mammalian Colon. Current Topics In Membranes 1987, 28: 457-468. DOI: 10.1016/s0070-2161(08)60425-6.Peer-Reviewed Original ResearchMammalian colonBasolateral cell membraneCell surfaceCell membraneElectrical gradientActive K secretionElectrochemical gradientK transportPotential-independent mechanismsIndependent mechanismsPotential-dependent mechanismK adaptationIntracellular KDependent mechanismK secretionShunt pathwayCarrier-mediated processCellsK leakPotassium adaptationPassive diffusionMembraneActive K transportAdaptationSecretion
1982
Demonstration of net potassium absorption in mammalian colon
Hayslett J, Halevy J, Pace P, Binder H. Demonstration of net potassium absorption in mammalian colon. American Journal Of Physiology 1982, 242: g209-g214. PMID: 7065184, DOI: 10.1152/ajpgi.1982.242.3.g209.Peer-Reviewed Original ResearchConceptsPotassium-deficient animalsNet potassium absorptionNet potassium secretionPlasma potassium levelsPotassium secretionNet potassium movementPotassium levelsPotassium-loaded animalsPotassium movementMammalian colonColon of controlLow-sodium solutionDistal colonPotassium absorptionSodium solutionControl animalsProximal segmentDistal lumensIntestinal transportNet secretionColonCarrier-mediated processSecretionAdditional studiesVivo studies