Glucagon secretion in acute and chronic pancreatitis.
Donowitz M, Hendler R, Spiro H, Binder H, Felig P. Glucagon secretion in acute and chronic pancreatitis. Annals Of Internal Medicine 1975, 83: 778-81. PMID: 1200523, DOI: 10.7326/0003-4819-83-6-778.Peer-Reviewed Original ResearchConceptsAcute pancreatitisPancreatic insufficiencyAlpha-cell responsivenessChronic pancreatic insufficiencyBasal glucagon levelsPancreatic glucagon concentrationsInfusion of alaninePrevious pancreatitisGlucagon responseAcute episodeGlucagon levelsGlucagon secretionChronic pancreatitisPlasma glucagonGlucagon concentrationsInitial episodeHealthy controlsPancreatitisCell responsivenessPatientsBasal statePrevious attacksSensitive indexInitial attackInsufficiency