Mechanism of potassium adaptation
Hayslett J, Binder H. Mechanism of potassium adaptation. American Journal Of Physiology 1982, 243: f103-f112. PMID: 7051849, DOI: 10.1152/ajprenal.1982.243.2.f103.Peer-Reviewed Original ResearchConceptsPotassium secretionPotassium adaptationChronic renal insufficiencyNa-K-ATPase activityAdministration of glucocorticoidsPotassium loadingNa-K-ATPaseTransepithelial potential differenceRenal insufficiencyPotassium excretionColonic mucosaExcretory loadDietary potassium loadingDistal nephronLarge intestinePotassium homeostasisDietary loadingElevated levelsPotassium pumpBasolateral portionEpitheliumCellular changesDistal portionSecretionBasolateral cell membrane