2005
Cross-Sectional Association of Kidney Function with Valvular and Annular Calcification: The Framingham Heart Study
Fox C, Larson M, Vasan R, Guo C, Parise H, Levy D, Leip E, O’Donnell C, D’Agostino R, Benjamin E. Cross-Sectional Association of Kidney Function with Valvular and Annular Calcification: The Framingham Heart Study. Journal Of The American Society Of Nephrology 2005, 17: 521-527. PMID: 16382018, DOI: 10.1681/asn.2005060627.Peer-Reviewed Original ResearchConceptsMitral annular calcificationAortic annular calcificationAnnular calcificationValvular calcificationKidney diseaseAortic sclerosisKidney functionPresence of MACTotal/HDL cholesterolVascular risk factor burdenRenal Disease Study equationEnd-stage kidney diseaseRisk factor burdenCardiovascular risk factorsCardiovascular disease eventsChronic kidney diseaseEarly kidney diseaseBody mass indexOnset of ESRDFramingham Offspring StudyTwo-dimensional echocardiographyFramingham Heart StudyDiastolic BPHDL cholesterolHypertension treatment
2003
Mitral Annular Calcification Predicts Cardiovascular Morbidity and Mortality
Fox C, Vasan R, Parise H, Levy D, O’Donnell C, D’Agostino R, Benjamin E. Mitral Annular Calcification Predicts Cardiovascular Morbidity and Mortality. Circulation 2003, 107: 1492-1496. PMID: 12654605, DOI: 10.1161/01.cir.0000058168.26163.bc.Peer-Reviewed Original ResearchConceptsMitral annular calcificationIncident CVDCVD deathCause deathAnnular calcificationHazard ratioPresence of MACIncident CVD eventsIncidence of CVDCardiovascular disease outcomesFramingham Heart Study subjectsMultivariable adjusted analysesSmall retrospective studiesCommunity-based cohortM-mode echocardiographyProportional hazards modelCardiovascular morbidityCVD eventsCVD morbidityCVD riskEchocardiographic assessmentAdjusted analysisRetrospective studyProspective dataIndependent association