Evaluating the clinical usefulness of platelet function testing: Considerations for the proper application and interpretation of performance measures
Dahlen J, Price M, Parise H, Gurbel P. Evaluating the clinical usefulness of platelet function testing: Considerations for the proper application and interpretation of performance measures. Thrombosis And Haemostasis 2013, 109: 808-816. PMID: 23254993, DOI: 10.1160/th12-08-0608.Peer-Reviewed Original ResearchConceptsPlatelet function testingFunction testingClinical usefulnessP2Y12 inhibitorsPharmacodynamic effectsPredictive valueFuture thrombotic eventsRate of thrombosisManagement of patientsPlatelet function testsNet reclassification improvementDiagnostic performance indicatorsPlatelet P2Y12 receptorPositive predictive valueDiagnostic performance measuresCardiovascular eventsHazard ratioThrombotic eventsRisk stratificationFunction testsPrognostic utilityAntiplatelet effectReclassification improvementRisk factorsP2Y12 receptor