Relationship between ST-segment resolution and anterior infarct size after primary percutaneous coronary intervention: analysis from the INFUSE-AMI trial
Dizon J, Brener S, Maehara A, Witzenbichler B, Biviano A, Godlewski J, Parise H, Dambrink J, Mehran R, Gibson C, Stone G. Relationship between ST-segment resolution and anterior infarct size after primary percutaneous coronary intervention: analysis from the INFUSE-AMI trial. European Heart Journal Acute Cardiovascular Care 2013, 3: 78-83. PMID: 24562806, PMCID: PMC3932776, DOI: 10.1177/2048872613508658.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAnterior Wall Myocardial InfarctionAntibodies, MonoclonalCoronary AngiographyElectrocardiographyFemaleHeart VentriclesHumansImmunoglobulin Fab FragmentsInfusions, IntravenousMagnetic Resonance Imaging, CineMaleMiddle AgedPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexTreatment OutcomeConceptsST-segment elevation myocardial infarctionST-segment resolutionST-segment elevationAnterior ST-segment elevation myocardial infarctionResidual ST-segment elevationDays post interventionINFUSE-AMI trialMin post interventionInfarct sizeMicrovascular obstructionPost interventionInfarct massBaseline ST-segment elevationPrimary percutaneous coronary interventionSimple ECG parametersUltimate infarct sizeElevation myocardial infarctionPercutaneous coronary interventionInfarct-related leadsTotal LV massQ wave changesSignificant Q wavesECG methodSingle leadBolus abciximabRelationship Between Myocardial Reperfusion, Infarct Size, and Mortality The INFUSE-AMI (Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction) Trial
Brener S, Maehara A, Dizon J, Fahy M, Witzenbichler B, Parise H, El-Omar M, Dambrink J, Mehran R, Oldroyd K, Gibson C, Stone G. Relationship Between Myocardial Reperfusion, Infarct Size, and Mortality The INFUSE-AMI (Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction) Trial. JACC Cardiovascular Interventions 2013, 6: 718-724. PMID: 23866184, DOI: 10.1016/j.jcin.2013.03.013.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAnterior Wall Myocardial InfarctionAntibodies, MonoclonalAnticoagulantsChi-Square DistributionCoronary AngiographyCoronary CirculationFemaleHumansImmunoglobulin Fab FragmentsMagnetic Resonance Imaging, CineMaleMicrocirculationMiddle AgedMyocardiumPercutaneous Coronary InterventionRecovery of FunctionRisk FactorsSuctionThrombectomyTime FactorsTreatment OutcomeConceptsINFUSE-AMI trialST-segment elevation myocardial infarctionElevation myocardial infarctionMBG 2/3Infarct sizeMicrocirculatory reperfusionMicrovascular obstructionEjection fractionMyocardial infarctionAnterior ST-segment elevation myocardial infarctionST-segment elevation myocardial infarction (STEMI) patientsElevation myocardial infarction patientsPrimary percutaneous coronary interventionManual thrombus aspirationPercutaneous coronary interventionSmaller infarct sizeMyocardial infarction patientsRate of deathBolus abciximabIntracoronary abciximabMBG 0/1Primary endpointCoronary interventionThrombus aspirationMyocardial reperfusionInfarct size and mortality in patients with proximal versus mid left anterior descending artery occlusion: The Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction (INFUSE-AMI) trial
Brener S, Witzenbichler B, Maehara A, Dizon J, Fahy M, El-Omar M, Dambrink J, Genereux P, Mehran R, Oldroyd K, Parise H, Gibson C, Stone G. Infarct size and mortality in patients with proximal versus mid left anterior descending artery occlusion: The Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction (INFUSE-AMI) trial. American Heart Journal 2013, 166: 64-70. PMID: 23816023, DOI: 10.1016/j.ahj.2013.03.029.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAgedAntibodies, MonoclonalCardiac CatheterizationCoronary AngiographyCoronary StenosisCoronary VesselsElectrocardiographyFemaleHumansImmunoglobulin Fab FragmentsInjections, Intra-ArterialMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexSurvival RateThrombectomyTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionInfarct sizeMyocardial infarctionAnterior ST-segment elevation myocardial infarctionMyocardial blush grade 2/3Myocardial infarction flow 3Primary percutaneous coronary interventionINFUSE-AMI trialMyocardial Infarction trialPrimary end pointST-segment resolutionPercutaneous coronary interventionSeptal perforator branchExtent of myocardiumEffect of ICSBivalirudin anticoagulationBolus abciximabFinal ThrombolysisIntracoronary abciximabKillip classLAD infarctsReperfusion therapyArtery occlusionCoronary intervention