Chapter Six The Role of Guanfacine as a Therapeutic Agent to Address Stress-Related Pathophysiology in Cocaine-Dependent Individuals
Fox H, Sinha R. Chapter Six The Role of Guanfacine as a Therapeutic Agent to Address Stress-Related Pathophysiology in Cocaine-Dependent Individuals. Advances In Pharmacology 2014, 69: 217-265. PMID: 24484979, PMCID: PMC4017947, DOI: 10.1016/b978-0-12-420118-7.00006-8.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsAdaptive goal-directed behaviorNegative emotional statesGoal-directed behaviorCompulsive drug useDrug-seeking behaviorCocaine dependenceStress-related pathophysiologyCognitive regulationNegative affectEmotional controlEmotional statesAnxiety pathophysiologyPrefrontal cortexDrugs of abuseNeural systemsBehavioral processesRecent research findingsBrain regionsCocaine addictionGuanfacinePolydrug abusersResearch findingsCocaine withdrawal symptomsDrug use