Aging of the human innate immune system in HIV infection
Zapata HJ, Shaw AC. Aging of the human innate immune system in HIV infection. Current Opinion In Immunology 2014, 29: 127-136. PMID: 24997358, PMCID: PMC4145838, DOI: 10.1016/j.coi.2014.06.007.Peer-Reviewed Original ResearchConceptsHIV infectionHIV-negative adultsChronic inflammatory statePro-inflammatory environmentInnate immune recognitionInnate immune responseInnate immune systemHuman innate immune systemMicrobial translocationImmune agingInflammatory stateImmune responseEndogenous ligandImmune recognitionImmune systemInfectionMultiple factorsEarly stagesHIV