2016
Menstrual and Reproductive Factors, Hormone Use, and Risk of Pancreatic Cancer
Lujan-Barroso L, Zhang W, Olson SH, Gao YT, Yu H, Baghurst PA, Bracci PM, Bueno-de-Mesquita H, Foretová L, Gallinger S, Holcatova I, Janout V, Ji BT, Kurtz RC, La Vecchia C, Lagiou P, Li D, Miller AB, Serraino D, Zatonski W, Risch HA, Duell EJ. Menstrual and Reproductive Factors, Hormone Use, and Risk of Pancreatic Cancer. Pancreas 2016, 45: 1401-1410. PMID: 27088489, PMCID: PMC5065728, DOI: 10.1097/mpa.0000000000000635.Peer-Reviewed Original ResearchConceptsHormone replacement therapyPancreatic cancerHRT useOdds ratioReproductive factorsInternational Pancreatic Cancer Case-Control ConsortiumRisk of PCLarge pooled analysisPancreatic Cancer Case-Control ConsortiumConfidence intervalsCase-control studySignificant inverse associationLogistic regression modelsPostmenopausal womenHormone useControl womenReplacement therapyPooled analysisInverse associationHysterectomyPooled estimatesRelevant covariatesExogenous hormonesWomenRisk
2015
Ovarian cancer survival by tumor dominance, a surrogate for site of origin
Ivanova A, Loo A, Tworoger S, Crum CP, Fan I, McLaughlin JR, Rosen B, Risch H, Narod SA, Kotsopoulos J. Ovarian cancer survival by tumor dominance, a surrogate for site of origin. Cancer Causes & Control 2015, 26: 601-608. PMID: 25771796, PMCID: PMC4561551, DOI: 10.1007/s10552-015-0547-y.Peer-Reviewed Original ResearchConceptsDominant tumorHazard ratioFallopian tubeEstrogen hormone replacement therapyConclusionThese preliminary findingsHormone replacement therapyDistal fallopian tubeRisk of deathEpithelial ovarian cancerOvarian cancer survivalConfidence intervalsProportional hazards modelSite of originTubal originWorse survivalReplacement therapyOvarian tumorsCancer survivalOvarian cancerPathology reportsOnly subtypeBRCA1/2 mutationsHazards modelObjectivesRecent studiesTumors
1996
Estrogen Replacement Therapy and Risk of Epithelial Ovarian Cancer
Risch H. Estrogen Replacement Therapy and Risk of Epithelial Ovarian Cancer. Gynecologic Oncology 1996, 63: 254-257. PMID: 8910636, DOI: 10.1006/gyno.1996.0315.Peer-Reviewed Original ResearchConceptsEstrogen replacement therapyEpithelial ovarian cancerOvarian cancerReplacement therapyRelative oddsInvasive epithelial ovarian cancerMultivariate logistic regression analysisHistology-specific analysisNonmucinous ovarian cancerOral contraceptive usageLogistic regression analysisERT usageERT useMucinous tumorsTumor histologyMenopausal womenSerous carcinomaEndometrioid carcinomaHistologic groupsNonmucinous typeCancerCarcinomaRegression analysisPopulation controlsTherapy