2014
Genes–Environment Interactions in Obesity- and Diabetes-Associated Pancreatic Cancer: A GWAS Data Analysis
Tang H, Wei P, Duell EJ, Risch HA, Olson SH, Bueno-de-Mesquita HB, Gallinger S, Holly EA, Petersen GM, Bracci PM, McWilliams RR, Jenab M, Riboli E, Tjønneland A, Boutron-Ruault MC, Kaaks R, Trichopoulos D, Panico S, Sund M, Peeters PH, Khaw KT, Amos CI, Li D. Genes–Environment Interactions in Obesity- and Diabetes-Associated Pancreatic Cancer: A GWAS Data Analysis. Cancer Epidemiology Biomarkers & Prevention 2014, 23: 98-106. PMID: 24136929, PMCID: PMC3947145, DOI: 10.1158/1055-9965.epi-13-0437-t.Peer-Reviewed Original ResearchConceptsPancreatic cancerIngenuity Pathway AnalysisSingle nucleotide polymorphismsAssociation of obesityPancreatic Cancer Case-Control ConsortiumRisk of obesityAlterable risk factorsPancreatic cancer riskRisk factor dataLogistic regression modelsGenome-wide levelAdditional large datasetsMajor contributing genesInsulin resistanceRisk factorsInflammatory responseCancer riskGene-environment interactionsObesityGene-environment interaction analysisSignificant interactionDiabetesGWAS data analysisCancerGenetic susceptibility
2013
Dietary Energy Density Is Positively Associated with Risk of Pancreatic Cancer in Urban Shanghai Chinese 1,2
Wang J, Zhang W, Sun L, Yu H, Ni QX, Risch HA, Gao YT. Dietary Energy Density Is Positively Associated with Risk of Pancreatic Cancer in Urban Shanghai Chinese 1,2. Journal Of Nutrition 2013, 143: 1626-1629. PMID: 23902959, PMCID: PMC3771813, DOI: 10.3945/jn.113.178129.Peer-Reviewed Original ResearchConceptsCase-control studyPancreatic cancerDietary energy densityRisk factorsPopulation-based case-control studyFood frequency questionnaire dataIndependent risk factorPancreatic cancer riskType 2 diabetesAdjusted analysisProspective studyHighest quintileLowest quintileCancer riskNormal controlsRegular consumptionCancerOverall dietRiskQuintileShanghai ChineseUrban ShanghaiQuestionnaire dataObesityDiabetes