2013
Re-evaluation of ABO gene polymorphisms detected in a genome-wide association study and risk of pancreatic ductal adenocarcinoma in a Chinese population
Xu HL, Cheng JR, Zhang W, Wang J, Yu H, Ni QX, Risch HA, Gao YT. Re-evaluation of ABO gene polymorphisms detected in a genome-wide association study and risk of pancreatic ductal adenocarcinoma in a Chinese population. Cancer Communications 2013, 33: 68-73. PMID: 23816557, PMCID: PMC3884064, DOI: 10.5732/cjc.013.10060.Peer-Reviewed Original ResearchConceptsRisk of PDACPancreatic ductal adenocarcinomaCancer riskDuctal adenocarcinomaPopulation-based case-control studyChinese populationCase-control studyPancreatic cancer riskSignificant gene-environment interactionElevated cancer riskFatal malignancyPancreatic cancerTT carriersHealthy controlsGene-environment interactionsGene polymorphismsT alleleC alleleABO variantsWide association studyAssociation studiesMultifactor dimensionality reduction methodAdenocarcinomaRiskABO alleles
2012
Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations
Palmer AJ, Lochhead P, Hold GL, Rabkin CS, Chow WH, Lissowska J, Vaughan TL, Berry S, Gammon M, Risch H, El-Omar EM. Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations. European Journal Of Cancer Prevention 2012, 21: 541-544. PMID: 22805490, PMCID: PMC3460062, DOI: 10.1097/cej.0b013e3283529b79.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultBiomarkers, TumorCarcinoma, Squamous CellCase-Control StudiesEsophageal NeoplasmsFemaleGastrointestinal NeoplasmsGenetic Predisposition to DiseaseHumansMaleMembrane Transport ProteinsMucin-1Phosphoinositide Phospholipase CPolandPolymorphism, Single NucleotidePrognosisRisk FactorsUnited StatesWhite PeopleConceptsUpper gastrointestinal cancerOesophageal squamous cell cancerSquamous cell cancerGastrointestinal cancerCancer casesRisk of GCCaucasian populationCell cancerOdds ratioOesophageal squamous cell carcinomaSquamous cell carcinomaConfidence intervalsCase-control studyIntestinal histological typeGastric cancer casesHistological typeCell carcinomaSimilar associationGC casesChinese populationFirst studyCancerLarge genome-wide association studiesMUC1Adenocarcinoma