2000
Endometrial dating and determination of the window of implantation in healthy fertile women
Acosta A, Elberger L, Borghi M, Calamera J, Chemes H, Doncel G, Kliman H, Lema B, Lustig L, Papier S. Endometrial dating and determination of the window of implantation in healthy fertile women. Fertility And Sterility 2000, 73: 788-798. PMID: 10731542, DOI: 10.1016/s0015-0282(99)00605-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo ImplantationEndometriumEstradiolFemaleFollicle Stimulating HormoneGolgi ApparatusGrowth InhibitorsHumansImmunohistochemistryIntegrin alpha4beta1IntegrinsInterleukin-6Leukemia Inhibitory FactorLuteinizing HormoneLymphokinesMenstrual CycleMicroscopy, Electron, ScanningMucinsProspective StudiesReceptors, Interleukin-1Receptors, Interleukin-1 Type IReceptors, Lymphocyte HomingReceptors, ProgesteroneReceptors, VitronectinReference ValuesConceptsWindow of implantationLeukemia inhibitory factorLuteal phaseDay 22Day 20Endometrial datingInterleukin-1 receptor type IAssisted reproductive unitWhole luteal phaseProspective clinical studyHealthy fertile womenIL-1R tIReceptor type IMAG antibodyEndometrial biopsyFertile womenNormal womenImplantation windowP4 receptorReceptor expressionClinical studiesLH peakHealthy volunteersMAIN OUTCOMEImmunohistochemical determination
1990
Human trophoblast-extracellular matrix (ECM) interactions in vitro: ECM thickness modulates morphology and proteolytic activity.
Kliman HJ, Feinberg RF. Human trophoblast-extracellular matrix (ECM) interactions in vitro: ECM thickness modulates morphology and proteolytic activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 3057-3061. PMID: 2326266, PMCID: PMC53833, DOI: 10.1073/pnas.87.8.3057.Peer-Reviewed Original ResearchMeSH Keywords8-Bromo Cyclic Adenosine MonophosphateCell LineChoriocarcinomaExtracellular MatrixFemaleHumansMicroscopy, Electron, ScanningPregnancyTrophoblastsTumor Cells, CulturedUterine NeoplasmsConceptsJEG-3 human choriocarcinoma cellsMatrix degradationExtracellular matrix proteinsProteolytic activityHuman choriocarcinoma cellsExtracellular matrix degradationHuman trophoblastsCellular behaviorVascular developmentMatrix proteinsExtracellular matrix thicknessIntercellular processesMatrix interactionsUterine extracellular matrixExtracellular matrixProteolytic processesCellular morphologyUteroplacental vascular developmentChoriocarcinoma cellsECM thicknessStriking exampleMatrigelMillicell systemProteinMillicell filtersAggregation of dispersed human cytotrophoblastic cells: Lessons relevant to the morphogenesis of the placenta
Babalola G, Coutifaris C, Soto E, Kliman H, Shuman H, Strauss J. Aggregation of dispersed human cytotrophoblastic cells: Lessons relevant to the morphogenesis of the placenta. Developmental Biology 1990, 137: 100-108. PMID: 2295358, DOI: 10.1016/0012-1606(90)90011-7.Peer-Reviewed Original ResearchMeSH KeywordsCell AggregationChoriocarcinomaFemaleHumansMelanomaMicroscopy, ElectronMicroscopy, Electron, ScanningMorphogenesisPlacentaPregnancyTrophoblastsTumor Cells, CulturedUterine NeoplasmsConceptsJEG-3 cellsSuspension culturesCell-cell associationsJEG-3 choriocarcinoma cellsProtein synthesis inhibitorMulticellular structuresCellular aggregationHigh cell densityTrophoblast cell surfaceCytotrophoblast cellsHuman cytotrophoblastic cellsPlacenta formsCell typesRNA synthesisCell surfacePoor mediumChoriocarcinoma cellsCell linesSerum-free mediumActinomycin DOutgrowth culturesJEG-3Synthesis inhibitorExtent of aggregationFree medium