2023
Progress on the Endometrium
Frankfurter D, Kliman H. Progress on the Endometrium. Obstetrics And Gynecology Clinics Of North America 2023, 50: 677-694. PMID: 37914487, DOI: 10.1016/j.ogc.2023.09.002.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEmbryo ImplantationEndometriosisEndometriumFemaleHumansMammalsPregnancyTrophoblastsUterusConceptsAbsence of pregnancyEvidence-based approachEndometrial assessmentStromal maturationEndometrial proliferationEndometrial pathologyInflammatory mediatorsOvarian steroidsImplantation failureBlastocyst implantationEndometrial sloughingDiagnostic measuresEndometriumOffer hopeDynamic tissueDevelopmental markersSingle testTissueInternal reproductionMaturationEndometriosisPregnancyDecidualizationInfertilityUterus
2021
Loss of Cxcr4 in Endometriosis Reduces Proliferation and Lesion Number while Increasing Intraepithelial Lymphocyte Infiltration
Tal A, Tal R, Kliman HJ, Taylor HS. Loss of Cxcr4 in Endometriosis Reduces Proliferation and Lesion Number while Increasing Intraepithelial Lymphocyte Infiltration. American Journal Of Pathology 2021, 191: 1292-1302. PMID: 33964217, PMCID: PMC8261475, DOI: 10.1016/j.ajpath.2021.04.011.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell ProliferationEndometriosisEpithelial CellsFemaleIntraepithelial LymphocytesMiceReceptors, CXCR4ConceptsEndometriosis lesionsEpithelial compartmentLesion numberDisruption of CXCR4Intraepithelial lymphocyte infiltrationAdult female miceLoss of CXCR4CXCL12-CXCR4 axisTotal lesion areaProgesterone receptor promoterEndometriosis inductionLymphocyte infiltrationCXCR4 expressionFemale miceHost miceControl lesionsProestrus stageEpithelial proliferationImmune evasionCXCR4LesionsTherapeutic potentialLesion areaReduces ProliferationEpithelial cells
2002
Sexual Activity, Orgasm and Tampon Use Are Associated with a Decreased Risk for Endometriosis
Meaddough EL, Olive DL, Gallup P, Perlin M, Kliman HJ. Sexual Activity, Orgasm and Tampon Use Are Associated with a Decreased Risk for Endometriosis. Gynecologic And Obstetric Investigation 2002, 53: 163-169. PMID: 12053101, DOI: 10.1159/000058368.Peer-Reviewed Original Research
1996
Endocrinology and paracrinology
Arici A, Tazuke SI, Attar E, Kliman HJ, Olive DL. Endocrinology and paracrinology. Molecular Human Reproduction 1996, 2: 40-45. PMID: 9238656, DOI: 10.1093/molehr/2.1.40.Peer-Reviewed Original ResearchConceptsIL-8 mRNAIL-1 alphaEnzyme-linked immunosorbent assayIL-8 concentrationsPathogenesis of endometriosisInterleukin-8IL-8 proteinPeritoneal fluidMesothelial cellsPg/Human recombinant IL-1 alphaRecombinant IL-1 alphaNeutrophil chemotactic activityMinimal-mild endometriosisPeritoneal mesothelial cellsInterleukin-8 expressionCultured mesothelial cellsPotent angiogenic agentTNF-alpha treatmentModerate-severe endometriosisHuman mesothelial cellsNon-treated cellsControl patientsTime-dependent mannerTNF-alpha
1995
Endosalpingiosis found at laparoscopy for chronic pelvic pain**Presented at the 50th Annual Meeting of The American Fertility Society Meeting, San Antonio, Texas, November 5 to 10, 1994.
Keltz M, Kliman H, Arici A, Olive D. Endosalpingiosis found at laparoscopy for chronic pelvic pain**Presented at the 50th Annual Meeting of The American Fertility Society Meeting, San Antonio, Texas, November 5 to 10, 1994. Fertility And Sterility 1995, 64: 482-485. PMID: 7641898, DOI: 10.1016/s0015-0282(16)57780-2.Peer-Reviewed Original ResearchConceptsChronic pelvic painPelvic pain symptomsPelvic painPain symptomsAmerican Fertility Society MeetingYale-New Haven HospitalPatient undergoing laparoscopyUndergoing laparoscopyChronic painChronic pelvicEndosalpingiosisRetrospective analysisPainPathology specimensEndometriosisLaparoscopyPatientsSymptomsSociety meetingsAnnual MeetingSurgeryPelvicHospitalSan AntonioSurgeons