Featured Publications
Trophoblast inclusions in the human placenta: Identification, characterization, quantification, and interrelations of subtypes
Kliman HJ, Firestein MR, Hofmann KM, Milano KM, Holzer PH, Brink LT, Odendaal HJ, Fifer WP. Trophoblast inclusions in the human placenta: Identification, characterization, quantification, and interrelations of subtypes. Placenta 2020, 103: 172-176. PMID: 33152642, PMCID: PMC8448462, DOI: 10.1016/j.placenta.2020.10.014.Peer-Reviewed Original ResearchPlacental Pathology Findings in Unexplained Pregnancy Losses
Thompson B, Holzer P, Kliman H. Placental Pathology Findings in Unexplained Pregnancy Losses. Reproductive Sciences 2023, 31: 488-504. PMID: 37725247, PMCID: PMC10827979, DOI: 10.1007/s43032-023-01344-3.Peer-Reviewed Original ResearchWeeks of gestationCommon pathologic featureSmall placentaPathologic featuresPregnancy lossChorionic villiPlacental pathology findingsUnexplained lossUnexplained pregnancy lossAntepartum stillbirthPlacental examinationUnexplained stillbirthPathology findingsUnexplained miscarriagePrevalent abnormalityPathologic diagnosisClinical databaseStillbirthMiscarriagePathology slidesDiagnostic categoriesGenetic abnormalitiesClassification systemPlacentaPotential mechanisms
2012
Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia
Kliman HJ, Sammar M, Grimpel YI, Lynch SK, Milano KM, Pick E, Bejar J, Arad A, Lee JJ, Meiri H, Gonen R. Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia. Reproductive Sciences 2012, 19: 16-30. PMID: 21989657, DOI: 10.1177/1933719111424445.Peer-Reviewed Original ResearchConceptsPlacental protein 13Spiral arteriolesImmune cellsDecidual zoneProtein 13Decidual spiral arteriolesMaternal immune cellsWeeks of gestationElective pregnancy terminationHuman placental lactogenMaternal spiral arteriolesDecidual necrosisPregnancy terminationT cellsImmunohistochemical analysisDecidual veinsIntervillus spacePlacental lactogenInvasive trophoblastApoptosis markersPP13Chorionic villiNecrosisTrophoblastArterioles
2007
Reference Weights for Placentas Delivered before the 28th Week of Gestation
Hecht JL, Kliman HJ, Allred EN, Pflueger SM, Chang C, Doss BJ, Roberts D, Livasy CA, Bhan I, Zambrano E, Ross DW, Senagore P, Husain AN, Leviton A. Reference Weights for Placentas Delivered before the 28th Week of Gestation. Placenta 2007, 28: 987-990. PMID: 17573110, DOI: 10.1016/j.placenta.2007.04.009.Peer-Reviewed Original ResearchConceptsPost-menstrual weeksSingleton placentasBirth weightPlacenta weightBirth weight z-scoreStandard weight tableWeight z-scoreSmall birth weightWeeks of gestationFetal indicationsLive infantsGestational ageTwin placentasPoor perfusionGrowth restrictionLarger sample sizeZ-scorePlacentaWeeksFetal processesStandard weightReference weightSample sizePreeclampsiaPregnancy