Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism
Walker CK, Anderson KW, Milano KM, Ye S, Tancredi DJ, Pessah IN, Hertz-Picciotto I, Kliman HJ. Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism. Biological Psychiatry 2013, 74: 204-211. PMID: 23623455, PMCID: PMC3755347, DOI: 10.1016/j.biopsych.2013.03.006.Peer-Reviewed Original ResearchConceptsElevated riskPlacentas of childrenTrophoblast inclusionsUncomplicated term pregnanciesAutism spectrum disorderPositive likelihood ratioTargeted early interventionsNeurodevelopmental compromiseMultiparous womenTerm pregnancyRisk pregnanciesBiological childrenControl placentasBehavioral symptomsEarly interventionNeurodevelopmental vulnerabilityPlacentaCritical windowRisk statusPregnancyRiskNewbornsChildrenDevelopmental outcomesControl samples