1994
Transforming growth factor-beta stimulates trophoblast oncofetal fibronectin synthesis in vitro: implications for trophoblast implantation in vivo
Feinberg RF, Kliman HJ, Wang CL. Transforming growth factor-beta stimulates trophoblast oncofetal fibronectin synthesis in vitro: implications for trophoblast implantation in vivo. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 1241-1248. PMID: 8175984, DOI: 10.1210/jcem.78.5.8175984.Peer-Reviewed Original ResearchConceptsTGF beta 1TGF betaBeta 1Ability of trophoblastsAnti-TGF betaSevere alloimmune thrombocytopeniaThird trimester placentasPlatelet-poor serumDose-response analysisPregnancy tissueCord serumAlloimmune thrombocytopeniaCytokine presentUterine deciduaExtracellular matrixVillous syncytiotrophoblastTrimester placentaNormal serumHuman cytotrophoblastsGrowth factor-beta stimulatesOncofetal fibronectinNormal morphological differentiationCulture secreteStimulatory responseThrombocytopenic serum
1993
Tropho-uteronectin (tun): A unique oncofetal fibronectin deposited in the extracellular matrix of the tropho-uterine junction and regulated in vitro by cultured human trophoblast cells
Feinberg R, Kliman H. Tropho-uteronectin (tun): A unique oncofetal fibronectin deposited in the extracellular matrix of the tropho-uterine junction and regulated in vitro by cultured human trophoblast cells. Placenta 1993, 14: 167-179. DOI: 10.1016/s0143-4004(05)80292-9.Peer-Reviewed Original Research
1990
Human trophoblast-extracellular matrix (ECM) interactions in vitro: ECM thickness modulates morphology and proteolytic activity.
Kliman HJ, Feinberg RF. Human trophoblast-extracellular matrix (ECM) interactions in vitro: ECM thickness modulates morphology and proteolytic activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 3057-3061. PMID: 2326266, PMCID: PMC53833, DOI: 10.1073/pnas.87.8.3057.Peer-Reviewed Original ResearchConceptsJEG-3 human choriocarcinoma cellsMatrix degradationExtracellular matrix proteinsProteolytic activityHuman choriocarcinoma cellsExtracellular matrix degradationHuman trophoblastsCellular behaviorVascular developmentMatrix proteinsExtracellular matrix thicknessIntercellular processesMatrix interactionsUterine extracellular matrixExtracellular matrixProteolytic processesCellular morphologyUteroplacental vascular developmentChoriocarcinoma cellsECM thicknessStriking exampleMatrigelMillicell systemProteinMillicell filters
1989
Human trophoblast interaction with the extracellular matrix: A histologic assay system for studying trophoblast invasion
Feinberg R, Haimowitz J, Kliman H. Human trophoblast interaction with the extracellular matrix: A histologic assay system for studying trophoblast invasion. Placenta 1989, 10: 454-455. DOI: 10.1016/0143-4004(89)90058-1.Peer-Reviewed Original ResearchExtracellular matrix