Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial
Crockett S, Khashab M, Rex D, Grimm I, Moyer M, Rastogi A, Mackenzie T, Pohl H, Consortium L, Al-Kawas F, Antaki F, Aslanian H, Crockett S, Elias P, Elmunzer B, Gill J, Gordon S, Grimm I, Hasan M, Khashab M, Law R, Levenick J, Mackenzie T, Mathew A, Moyer M, Ortiz O, Pellise M, Pleskow D, Pohl H, Rastogi A, von Renteln D, Rex D, Sanaei O. Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial. Clinical Gastroenterology And Hepatology 2021, 20: 1757-1765.e4. PMID: 34971811, DOI: 10.1016/j.cgh.2021.12.036.Peer-Reviewed Original ResearchConceptsLarge serrated polypsEndoscopic mucosal resectionPost-procedure bleedingAdenomatous polypsBleeding rateProximal colonSerrated polypsControl groupLarge non-pedunculated polypsLimited clinical trial evidenceOverall serious adverse eventsPost-polypectomy bleeding rateDay of colonoscopyNon-pedunculated polypsSerious adverse eventsClinical trial evidenceRisk of bleedingColorectal cancer precursorsResection baseBleeding riskAdverse eventsMucosal resectionMulticenter trialPrimary outcomeProphylactic clippingFactors associated with complete clip closure after endoscopic mucosal resection of large colorectal polyps
Ortiz O, Rex DK, Grimm IS, Moyer MT, Hasan MK, Pleskow D, Elmunzer BJ, Khashab MA, Sanaei O, Al-Kawas FH, Gordon SR, Mathew A, Levenick JM, Aslanian H, Antaki F, von Renteln D, Crockett SD, Rastogi A, Gill JA, Law R, Wallace MB, Elias PA, MacKenzie TA, Pohl H, Pellisé M. Factors associated with complete clip closure after endoscopic mucosal resection of large colorectal polyps. Endoscopy 2021, 53: 1150-1159. PMID: 33291159, DOI: 10.1055/a-1332-6727.Peer-Reviewed Original ResearchMeSH KeywordsAgedColonic PolypsColonoscopyEndoscopic Mucosal ResectionFemaleHumansMaleSurgical InstrumentsConceptsEndoscopic mucosal resectionProphylactic clip closureLarge colorectal polypsClip closureMucosal defectsMucosal resectionColorectal polypsLarge polypsResection defectsComplete closureCommon adverse eventsSubmucosal liftingAdverse eventsBloc resectionMultivariable analysisProximal polypsSerrated histologyClip groupMAIN OUTCOMECLIP studyStudy aimPolyp sizeResectionPolypsPatients