1985
Normalization of Arterial Blood Gases after Treatment of Surfactant-Deficient Lambs with Tween 201–3
Jacobs H, Berry D, Duane G, Ikegami M, Jobe A, Jones S. Normalization of Arterial Blood Gases after Treatment of Surfactant-Deficient Lambs with Tween 201–3. American Journal Of Respiratory And Critical Care Medicine 1985, 132: 1313-8. PMID: 3935021, DOI: 10.1164/arrd.1985.132.6.1313.Peer-Reviewed Original ResearchConceptsPeak inspiratory pressurePulmonary surfactantAdequate ventilationMinimal surface tensionArterial blood gasesNormal lung functionMin of ageRespiratory failureLung functionLung complianceInspiratory pressureBlood gasesInfant ventilatorDays gestationAlveolar washControl animalsControl lambsPoor oxygenationSurfactant treatmentGas exchangeTreatmentVentilationLambsGestationVentilator
1983
Surfactant Pool Sizes and Severity of Respiratory Distress Syndrome in Prematurely Delivered Lambs1–3
Jobe A, Ikegami M, Jacobs H, Jones S. Surfactant Pool Sizes and Severity of Respiratory Distress Syndrome in Prematurely Delivered Lambs1–3. American Journal Of Respiratory And Critical Care Medicine 1983, 127: 751-5. PMID: 6552894, DOI: 10.1164/arrd.1983.127.6.751.Peer-Reviewed Original ResearchConceptsLung diseaseAlveolar washCompliant lungsMinimal surface tensionLow minimal surface tensionRespiratory distress syndromePeak inspiratory pressurePhosphatidylcholine pool sizesDays gestational ageSurfactant pool sizePremature lambsDistress syndromeGestational ageInspiratory pressureLung tissueRespiratory diseaseTidal volumeLung slicesSurfactant phosphatidylcholineTotal phosphatidylcholineDiseaseSeverityPool sizeRate of incorporationLung
1981
Sequential treatments of premature lambs with an artificial surfactant and natural surfactant.
Ikegami M, Jobe A, Jacobs H, Jones S. Sequential treatments of premature lambs with an artificial surfactant and natural surfactant. Journal Of Clinical Investigation 1981, 68: 491-496. PMID: 6790576, PMCID: PMC370823, DOI: 10.1172/jci110280.Peer-Reviewed Original ResearchConceptsArtificial surfactantPremature lambsGestational age lambsFetal lung fluidPO2 valuesGroups of lambsPressure-volume characteristicsMinimum surface tensionPremature lungAirway samplesNatural surfactant lipidAge lambsUntreated lambsMean pO2 valuesMinimal surface tensionLung fluidSurfactant lipidsSequential treatmentTreatmentNatural surfactantLambsHgPCO2 valuesAirwayLung