1986
Hemodynamic Effects of High Frequency Ventilation in Surfactant-Treated Preterm Lambs
Oguchi K, Baylen B, Ikegami M, Jacobs H, Berry D, Jobe A, Emmanouilides G. Hemodynamic Effects of High Frequency Ventilation in Surfactant-Treated Preterm Lambs. Neonatology 1986, 49: 21-28. PMID: 3753885, DOI: 10.1159/000242505.Peer-Reviewed Original ResearchConceptsHigh-frequency ventilationConventional ventilationHemodynamic effectsDuctus arteriosusPreterm lambsFrequency ventilationSame mean airway pressureLV end-diastolic volumeRight ductal shuntSurfactant-treated lambsMean airway pressureDeleterious hemodynamic effectsOrgan blood flowMin of ageEnd-diastolic volumeBlood gas valuesDays gestational ageLV stroke volumeBlood flow measurementsComparable ventilationDuctal shuntAirway pressureDuctal occlusionHemodynamic statusArterial pressure
1985
The Contractility and Performance of the Preterm Left Ventricle before and after Early Patent Ductus Arteriosus Occlusion in Surfactant- Treated Lambs
Baylen B, Ogata H, Oguchi K, Ikegami M, Jacobs H, Jobe A, Emmanouilides G. The Contractility and Performance of the Preterm Left Ventricle before and after Early Patent Ductus Arteriosus Occlusion in Surfactant- Treated Lambs. Pediatric Research 1985, 19: 1053-1058. PMID: 3840585, DOI: 10.1203/00006450-198510000-00022.Peer-Reviewed Original ResearchConceptsPatent ductus arteriosusSystemic blood flowEnd-diastolic volumeBlood flowDuctal shuntingSystemic perfusionPreterm lambsDuctus arteriosusEffective systemic blood flowVentricle end-diastolic volumeEarly hemodynamic responseLeft ventricle outputLeft-right shuntPatent ductus arteriosus occlusionLeft ventricular outputCardiac output stateLeft ventricle end-diastolic volumeOrgan blood flowDuctus arteriosus occlusionBlood flow measurementsDuctal shuntDuctal occlusionHemodynamic profileEjection fractionVentricular output
1984
Surfactant and pulmonary blood flow distributions following treatment of premature lambs with natural surfactant.
Jobe A, Ikegami M, Jacobs H, Jones S. Surfactant and pulmonary blood flow distributions following treatment of premature lambs with natural surfactant. Journal Of Clinical Investigation 1984, 73: 848-856. PMID: 6546766, PMCID: PMC425089, DOI: 10.1172/jci111280.Peer-Reviewed Original ResearchConceptsPieces of lungBlood flow distributionPulmonary blood flow distributionLungs of lambsMechanical ventilationRight ductal shuntPulmonary blood flowConstant distending pressurePeriod of ventilationGroups of lambsDuctal shuntPremature lambsAtelectatic areasSurfactant instillationVentricular outputTracheal instillationDistending pressureBlood flowLungLung piecesVentilationInstillationBirthLambsNatural surfactant