1989
Pulmonary function tests and fluid balance in neonates with chronic lung disease during dexamethasone treatment.
Gladstone I, Ehrenkranz R, Jacobs H. Pulmonary function tests and fluid balance in neonates with chronic lung disease during dexamethasone treatment. Pediatrics 1989, 84: 1072-6. PMID: 2587137, DOI: 10.1542/peds.84.6.1072.Peer-Reviewed Original ResearchConceptsPulmonary function testsChronic lung diseaseFunction testsLung diseaseFluid balanceTotal pulmonary resistanceHours of treatmentFirst dosePulmonary resistanceUrine outputGestational ageRespiratory statusBirth weightExpiratory timeDexamethasone treatmentClinical teamDynamic complianceFluid shiftsInfantsDexamethasoneExtubationSignificant differencesTreatmentDiseaseHours
1984
Lack of correlation of severity of lung disease with the phosphatidylcholine concentration in fetal lung fluid from premature lambs at 133-136 days gestational age.
Jobe A, Jacobs H, Ikegami M. Lack of correlation of severity of lung disease with the phosphatidylcholine concentration in fetal lung fluid from premature lambs at 133-136 days gestational age. Journal Of Developmental Physiology 1984, 6: 417-21. PMID: 6568247.Peer-Reviewed Original ResearchConceptsFetal lung fluidPeak inspiratory pressureDays gestational ageLung diseaseLung fluidPremature lambsGestational ageInspiratory pressureConcentration of phosphatidylcholinePhosphatidylcholine concentrationNarrow gestational age rangePhosphatidylcholine pool sizesGestational age rangeTime of deliveryLung compliance valuesMechanical ventilationAlveolar washTotal phosphatidylcholineDiseaseAge rangeSeverityLack of correlationAgeLambsCompliance values
1983
Surfactant Pool Sizes and Severity of Respiratory Distress Syndrome in Prematurely Delivered Lambs1–3
Jobe A, Ikegami M, Jacobs H, Jones S. Surfactant Pool Sizes and Severity of Respiratory Distress Syndrome in Prematurely Delivered Lambs1–3. American Journal Of Respiratory And Critical Care Medicine 1983, 127: 751-5. PMID: 6552894, DOI: 10.1164/arrd.1983.127.6.751.Peer-Reviewed Original ResearchConceptsLung diseaseAlveolar washCompliant lungsMinimal surface tensionLow minimal surface tensionRespiratory distress syndromePeak inspiratory pressurePhosphatidylcholine pool sizesDays gestational ageSurfactant pool sizePremature lambsDistress syndromeGestational ageInspiratory pressureLung tissueRespiratory diseaseTidal volumeLung slicesSurfactant phosphatidylcholineTotal phosphatidylcholineDiseaseSeverityPool sizeRate of incorporationLung