Cardiovascular Effects of Surfactant Suspensions Given by Tracheal Instillation to Premature Lambs
Jobe A, Jacobs H, Ikegami M, Jones S. Cardiovascular Effects of Surfactant Suspensions Given by Tracheal Instillation to Premature Lambs. Pediatric Research 1983, 17: 444-448. PMID: 6553821, DOI: 10.1203/00006450-198306000-00002.Peer-Reviewed Original ResearchConceptsSurfactant instillationPremature lambsOnly ventilator settingPulmonary artery pressureDays gestational ageSurfactant treatmentArtery pressureCesarean sectionRespiratory supportCardiovascular effectsLung functionGestational ageCardiovascular statusInspiratory pressureRespiratory statusTransient deteriorationCardiac outputAortic pressureTracheal instillationVentilator settingsInfant ventilatorRegional bloodHeart rateInstillationBody weightLeft ventricular performance and regional blood flows before and after ductus arteriosus occlusion in premature lambs treated with surfactant.
Baylen B, Ogata H, Ikegami M, Jacobs H, Jobe A, Emmanouilides G. Left ventricular performance and regional blood flows before and after ductus arteriosus occlusion in premature lambs treated with surfactant. Circulation 1983, 67: 837-843. PMID: 6687448, DOI: 10.1161/01.cir.67.4.837.Peer-Reviewed Original ResearchConceptsPatent ductus arteriosusSystemic blood flowBlood flowVentricular performanceLV end-diastolic pressureEarly pathologic manifestationsOvert LV dysfunctionRight PDA shuntEnd-diastolic pressureHours of lifeLeft ventricular performanceRadionuclide-labeled microspheresDuctus arteriosus occlusionRegional blood flowPDA shuntLV dysfunctionPremature lambsRight shuntDuctus arteriosusEjection fractionPreterm lambsHemodynamic consequencesCardiac outputLeft ventriculographyPathologic manifestations