2023
Foundation models for generalist medical artificial intelligence
Moor M, Banerjee O, Abad Z, Krumholz H, Leskovec J, Topol E, Rajpurkar P. Foundation models for generalist medical artificial intelligence. Nature 2023, 616: 259-265. PMID: 37045921, DOI: 10.1038/s41586-023-05881-4.Peer-Reviewed Original ResearchConceptsMedical AILarge medical datasetsMedical artificial intelligenceArtificial intelligence modelsImage annotationMedical datasetsArtificial intelligenceElectronic health recordsAI devicesIntelligence modelsTraining datasetDiverse datasetsExpressive outputHealth recordsRapid developmentDatasetFree-text explanationsMedical modalitiesNew paradigmMedical textsAITechnical capabilitiesDiverse setNewfound capabilitiesCapability
2009
Association of Physician Certification and Outcomes Among Patients Receiving an Implantable Cardioverter-Defibrillator
Curtis JP, Luebbert JJ, Wang Y, Rathore SS, Chen J, Heidenreich PA, Hammill SC, Lampert RI, Krumholz HM. Association of Physician Certification and Outcomes Among Patients Receiving an Implantable Cardioverter-Defibrillator. JAMA 2009, 301: 1661-1670. PMID: 19383957, PMCID: PMC2805129, DOI: 10.1001/jama.2009.547.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac ElectrophysiologyCertificationClinical CompetenceDefibrillators, ImplantableFemaleHumansIntraoperative ComplicationsLogistic ModelsMaleMedicineMiddle AgedOutcome and Process Assessment, Health CarePhysiciansPostoperative ComplicationsProsthesis ImplantationRegistriesRetrospective StudiesSpecializationTreatment OutcomeUnited StatesConceptsCRT-D devicesThoracic surgeonsICD implantationPhysician certificationImplantable cardioverter-defibrillator (ICD) proceduresRetrospective cohort studyCardiac resynchronization therapyPatients meeting criteriaRisk of complicationsProcedural complication rateImplantable cardioverter defibrillatorHierarchical logistic regression modelsLogistic regression modelsCohort studyComplication rateICD RegistryResynchronization therapyProcedural complicationsIndependent associationPhysician specialtyCardioverter defibrillatorHigh riskPatientsMeeting criteriaNonelectrophysiologists
2005
Physician specialty and mortality among elderly patients hospitalized with heart failure
Foody JM, Rathore SS, Wang Y, Herrin J, Masoudi FA, Havranek EP, Krumholz HM. Physician specialty and mortality among elderly patients hospitalized with heart failure. The American Journal Of Medicine 2005, 118: 1120-1125. PMID: 16194643, DOI: 10.1016/j.amjmed.2005.01.075.Peer-Reviewed Original ResearchConceptsHeart failureFamily physiciansGeneral physiciansSpecialty careDay of admissionCause mortalityCardiology consultationElderly patientsPrimary outcomePhysician specialtyMedicare beneficiariesMortality ratePatientsCardiologistsPhysiciansMortalityInternistsCareOutcomesConsultationFailureDaysSpecialtiesAdmission
2001
Physician characteristics and the initiation of beta-adrenergic blocking agent therapy after acute myocardial infarction in a managed care population.
Fehrenbach SN, Budnitz DS, Gazmararian JA, Krumholz HM. Physician characteristics and the initiation of beta-adrenergic blocking agent therapy after acute myocardial infarction in a managed care population. The American Journal Of Managed Care 2001, 7: 717-23. PMID: 11464429.Peer-Reviewed Original ResearchConceptsBeta-adrenergic blocking agentsAcute myocardial infarctionBeta-adrenergic blocking agent therapyRegion of hospitalizationFamily practice physiciansPhysician characteristicsBlocking agentMyocardial infarctionHospital dischargeAgent therapyPractice physiciansPercent of patientsRetrospective administrative data analysisPatient agePatient characteristicsMedication claimsStudy cohortCare populationCardiac treatmentAdministrative data analysisInfarctionMultivariate modelPhysiciansHospitalizationCare organizationsRacial Differences in the Use of Cardiac Catheterization after Acute Myocardial Infarction
Chen J, Rathore S, Radford M, Wang Y, Krumholz H. Racial Differences in the Use of Cardiac Catheterization after Acute Myocardial Infarction. New England Journal Of Medicine 2001, 344: 1443-1449. PMID: 11346810, DOI: 10.1056/nejm200105103441906.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac catheterizationBlack patientsWhite patientsMyocardial infarctionCooperative Cardiovascular ProjectPatterns of careAdjusted mortality rateRacial differencesBlack physiciansStudy cohortCatheterizationInfarctionMedicare beneficiariesMortality ratePatientsPhysiciansWhite physiciansLower ratesSignificant interactionCohortRaceDifferencesCare