2023
Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction
Zhu C, Dreyer R, Li F, Spatz E, Caraballo‐Cordovez C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2023, 12: e030031. PMID: 37589125, PMCID: PMC10547344, DOI: 10.1161/jaha.123.030031.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac-specific qualityGeneric health statusMyocardial infarctionBaseline healthMarital stressHealth outcomesHealth statusWorse patient-reported outcomesMental healthYoung adultsObservational cohort studyPatient-reported outcomesSocioeconomic factorsWorse mental healthReadmission 1Cause readmissionCohort studyYounger patientsRoutine screeningDepressive symptomsGreater oddsAnginaMale participantsOutcomes
2018
Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China
Lu Y, Zhang H, Wang Y, Zhou T, Welsh J, Liu J, Guan W, Li J, Li X, Zheng X, Spertus JA, Masoudi FA, Krumholz HM, Jiang L. Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China. JAMA Network Open 2018, 1: e185446. PMID: 30646292, PMCID: PMC6324328, DOI: 10.1001/jamanetworkopen.2018.5446.Peer-Reviewed Original ResearchConceptsStable coronary artery diseaseAcute myocardial infarctionCoronary artery diseaseSeattle Angina QuestionnairePercutaneous coronary interventionClinical improvementSmall clinical improvementAngina symptomsUnstable anginaArtery diseaseHealth statusCoronary interventionSymptom burdenMyocardial infarctionSAQ scoresSAQ angina frequency scorePatient-reported health statusPercutaneous coronary intervention (PCI) proceduresSelf-reported health statusAngina frequency scoreMulticenter cohort studyGreater clinical improvementSubstantial clinical improvementIschemic heart diseaseCoronary intervention procedures
2015
Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention
Desai NR, Bradley SM, Parzynski CS, Nallamothu BK, Chan PS, Spertus JA, Patel MR, Ader J, Soufer A, Krumholz HM, Curtis JP. Appropriate Use Criteria for Coronary Revascularization and Trends in Utilization, Patient Selection, and Appropriateness of Percutaneous Coronary Intervention. JAMA 2015, 314: 2045-2053. PMID: 26551163, PMCID: PMC5459470, DOI: 10.1001/jama.2015.13764.Peer-Reviewed Original ResearchConceptsNonacute percutaneous coronary interventionPercutaneous coronary interventionAppropriate use criteriaInappropriate percutaneous coronary interventionHospital-level variationCoronary revascularizationPatient selectionUse criteriaCoronary interventionStudy periodAppropriateness of PCINational Cardiovascular Data Registry CathPCI RegistryProportion of PCIsMultivessel coronary artery diseaseHigh-risk findingsCoronary artery diseaseAnnual PCI volumesCross-sectional analysisAngina severityAntianginal medicationsAcute indicationsCathPCI RegistryArtery diseasePCI volumePCI proceduresGender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis
Dreyer RP, Smolderen KG, Strait KM, Beltrame JF, Lichtman JH, Lorenze NP, D’Onofrio G, Bueno H, Krumholz HM, Spertus JA. Gender differences in pre-event health status of young patients with acute myocardial infarction: A VIRGO study analysis. European Heart Journal Acute Cardiovascular Care 2015, 5: 43-54. PMID: 25681487, PMCID: PMC4658311, DOI: 10.1177/2048872615568967.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPrior coronary artery diseaseCoronary artery diseaseHealth statusMyocardial infarctionYounger patientsArtery diseaseCoronary artery disease historyDisease-specific health statusAcute myocardial infarction patientsAggressive symptom controlCornerstone of careWorse physical functionBaseline health statusMedical record abstractionVisual analog scaleHealth status outcomesMyocardial infarction patientsDisease-specific measuresMean health scoresLogistic regression analysisQuality of lifeHealth status informationGender differencesSymptom control
2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons
Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, Douglas PS, Foody JM, Gerber TC, Hinderliter AL, King SB, Kligfield PD, Krumholz HM, Kwong RY, Lim MJ, Linderbaum JA, Mack MJ, Munger MA, Prager RL, Sabik JF, Shaw LJ, Sikkema JD, Smith CR, Smith SC, Spertus JA, Williams SV. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Journal Of The American College Of Cardiology 2012, 60: e44-e164. PMID: 23182125, DOI: 10.1016/j.jacc.2012.07.013.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAdrenergic beta-AntagonistsAlcohol DrinkingAngina PectorisBody WeightCholesterol, LDLClopidogrelComorbidityCost of IllnessDepressionDiabetes ComplicationsDisease ManagementElectrocardiographyExerciseExercise TestGlycated HemoglobinHealth BehaviorHumansHypertensionLife StyleMyocardial InfarctionMyocardial IschemiaMyocardial RevascularizationPhysical ExaminationPlatelet Aggregation InhibitorsPractice Guidelines as TopicQuality of LifeRisk AssessmentRisk FactorsRisk Reduction BehaviorSmoking CessationTiclopidineConceptsAmerican CollegeAmerican Heart Association Task ForcePreventive Cardiovascular Nurses AssociationCardiology Foundation/American Heart Association Task ForceManagement of patientsThoracic surgeryPractice guidelinesCardiovascular AngiographyThoracic surgeonsSTS guidelinesA ReportNurses AssociationAmerican AssociationTask ForceAssociationGuidelinesPatientsSurgeryAngiographyPhysiciansDiagnosisSurgeonsDevelopment of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention
Curtis JP, Geary LL, Wang Y, Chen J, Drye EE, Grosso LM, Spertus JA, Rumsfeld JS, Weintraub WS, Masoudi FA, Brindis RG, Krumholz HM. Development of 2 Registry-Based Risk Models Suitable for Characterizing Hospital Performance on 30-Day All-Cause Mortality Rates Among Patients Undergoing Percutaneous Coronary Intervention. Circulation Cardiovascular Quality And Outcomes 2012, 5: 628-637. PMID: 22949491, DOI: 10.1161/circoutcomes.111.964569.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAged, 80 and overAngina PectorisChi-Square DistributionComorbidityFemaleHeart DiseasesHospital MortalityHospitalsHumansLogistic ModelsMaleMyocardial InfarctionOdds RatioOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionQuality Indicators, Health CareRegistriesRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionRisk-standardized mortality ratesElevation myocardial infarctionPatient mortality ratesMyocardial infarctionMortality rateCardiogenic shockCoronary interventionDerivation cohortHospital risk-standardized mortality ratesCause mortality ratesAdministrative claims dataQuality of careHierarchical logistic regression modelsNational Quality ForumLogistic regression modelsObserved mortality rateCathPCI RegistryNational HospitalClaims dataInfarctionPatientsQuality ForumFinal model
2011
Angina frequency after myocardial infarction and quality of life in older versus younger adults: The Prospective Registry Evaluating Myocardial Infarction: Event and Recovery study
Longmore RB, Spertus JA, Alexander KP, Gosch K, Reid KJ, Masoudi FA, Krumholz HM, Rich MW. Angina frequency after myocardial infarction and quality of life in older versus younger adults: The Prospective Registry Evaluating Myocardial Infarction: Event and Recovery study. American Heart Journal 2011, 161: 631-638. PMID: 21392621, DOI: 10.1016/j.ahj.2010.12.005.Peer-Reviewed Original ResearchConceptsSeattle Angina QuestionnaireCoronary artery diseaseYounger patientsAngina controlAngina frequencyOlder patientsArtery diseaseMyocardial infarctionChronic coronary artery diseaseSAQ angina frequency scoreYoung adultsAngina frequency scoreGreater HRQL improvementsHealth-related qualityQuality of lifeBaseline HRQLHRQL improvementResidual anginaAngina QuestionnaireProspective registryStable patientsMI survivorsRecent MISurvivors increasesHRQL
2010
Meta-analysis: effects of percutaneous coronary intervention versus medical therapy on angina relief.
Wijeysundera HC, Nallamothu BK, Krumholz HM, Tu JV, Ko DT. Meta-analysis: effects of percutaneous coronary intervention versus medical therapy on angina relief. Annals Of Internal Medicine 2010, 152: 370-9. PMID: 20231568, DOI: 10.7326/0003-4819-152-6-201003160-00007.Peer-Reviewed Original ResearchMeSH KeywordsAngina PectorisAngioplasty, Balloon, CoronaryCoronary DiseaseDrug-Eluting StentsHumansMyocardial InfarctionRegression AnalysisConceptsPercutaneous coronary interventionStable coronary artery diseaseEvidence-based medicationsCoronary artery diseaseMedical therapyAngina reliefCoronary interventionArtery diseaseIndependent reviewersTrials of PCIIncremental benefitRecent myocardial infarctionInclusion of patientsEvidence-based therapiesStudy-level dataDrug-eluting stentsRandom-effects modelMeta-regression analysisLong-term usePatient characteristicsCochrane LibraryContemporary trialsLanguage restrictionsMyocardial infarctionRecent trials
2009
Factors associated with racial differences in myocardial infarction outcomes.
Spertus JA, Jones PG, Masoudi FA, Rumsfeld JS, Krumholz HM. Factors associated with racial differences in myocardial infarction outcomes. Annals Of Internal Medicine 2009, 150: 314-24. PMID: 19258559, PMCID: PMC3387537, DOI: 10.7326/0003-4819-150-5-200903030-00007.Peer-Reviewed Original ResearchConceptsQuality of lifeMyocardial infarction outcomesSite of careBlack patientsMyocardial infarctionRacial differencesPost-myocardial infarction outcomesBaseline cardiac riskHigher unadjusted mortalityProspective cohort studySeattle Angina QuestionnaireAngina QuestionnaireCardiovascular outcomesCause mortalityRehospitalization ratesUnadjusted mortalityCohort studyHospital factorsPatient characteristicsWhite patientsCardiac dysfunctionCardiac riskPatient factorsPatient's symptomsNational Heart
2008
Angina at 1 Year After Myocardial Infarction: Prevalence and Associated Findings
Maddox TM, Reid KJ, Spertus JA, Mittleman M, Krumholz HM, Parashar S, Ho PM, Rumsfeld JS. Angina at 1 Year After Myocardial Infarction: Prevalence and Associated Findings. JAMA Internal Medicine 2008, 168: 1310-1316. PMID: 18574088, DOI: 10.1001/archinte.168.12.1310.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina PectorisFemaleHumansMaleMiddle AgedMyocardial InfarctionPrevalenceRisk FactorsTime FactorsConceptsAngina 1 yearMyocardial infarctionDepressive symptomsPrior coronary artery bypass graft surgeryCoronary artery bypass graft surgeryArtery bypass graft surgeryRecurrent rest anginaBypass graft surgeryPatients 1 yearQuestionnaire 1 yearAcute myocardial infarctionMultivariate regression modelingGraft surgeryIndex hospitalizationRest anginaMulticenter cohortPersistent smokingAssociated findingMI presentationModifiable factorsClinical historyOutpatient treatmentAnginaInpatient treatmentPatientsThe influence of age on health status outcomes after acute myocardial infarction
Ho PM, Eng MH, Rumsfeld JS, Spertus JA, Peterson PN, Jones PG, Peterson ED, Alexander KP, Havranek EP, Krumholz HM, Masoudi FA. The influence of age on health status outcomes after acute myocardial infarction. American Heart Journal 2008, 155: 855-861. PMID: 18440332, DOI: 10.1016/j.ahj.2007.11.032.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYears of ageSurvivors of AMIHealth status outcomesOlder patientsBetter HRQLHigh mortalityMyocardial infarctionStatus outcomesSeattle Angina QuestionnaireBaseline health statusHealth-related qualityNumber of patientsInfluence of ageAngina burdenBaseline anginaAngina QuestionnaireAngina symptomsClinical characteristicsProspective cohortYounger patientsMultivariable analysisRisk factorsSpectrum of ageHRQL
2007
2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina
Fraker TD, Fihn SD, Gibbons R, Abrams J, Chatterjee K, Daley J, Deedwania P, Douglas J, Ferguson T, Gardin J, O'Rourke R, Williams S, Smith S, Jacobs A, Adams C, Anderson J, Buller C, Creager M, Ettinger S, Halperin J, Hunt S, Krumholz H, Kushner F, Lytle B, Nishimura R, Page R, Riegel B, Tarkington L, Yancy C. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to Develop the Focused Update of the 2002 Guidelines for the Management of Patients With Chronic Stable Angina. Journal Of The American College Of Cardiology 2007, 50: 2264-2274. PMID: 18061078, DOI: 10.1016/j.jacc.2007.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAngina PectorisCardiovascular AgentsChronic DiseaseDietExerciseHumansHypolipidemic AgentsLife Style2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina
Fraker TD, Fihn SD, Committee W, MEERS 2, Gibbons R, Abrams J, Chatterjee K, Daley J, Deedwania P, Douglas J, Ferguson T, Gardin JM, O’Rourke R, Pasternak R, Williams S, Smith S, Jacobs A, Adams C, Anderson J, Buller C, Creager M, Ettinger S, Halperin J, Hunt S, Krumholz H, Kushner F, Lytle B, Nishimura R, Page R, Riegel B, Tarkington L, Yancy C. 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina. Circulation 2007, 116: 2762-2772. PMID: 17998462, DOI: 10.1161/circulationaha.107.187930.Peer-Reviewed Original ResearchAssociation Between Angina and Treatment Satisfaction after Myocardial Infarction
Plomondon ME, Magid DJ, Masoudi FA, Jones PG, Barry LC, Havranek E, Peterson ED, Krumholz HM, Spertus JA, Rumsfeld JS, for the PREMIER Investigators. Association Between Angina and Treatment Satisfaction after Myocardial Infarction. Journal Of General Internal Medicine 2007, 23: 1-6. PMID: 17955303, PMCID: PMC2173926, DOI: 10.1007/s11606-007-0430-y.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina PectorisFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionPatient SatisfactionConceptsLower treatment satisfactionSeattle Angina QuestionnaireTreatment satisfactionMyocardial infarctionPresence of anginaResultsSixty-two percentQuality of carePersistent anginaAngina QuestionnaireClinical factorsMultivariable analysisMI patientsNew anginaUnadjusted analysesBackgroundPatient satisfactionAnginaMultivariable regressionTransient anginaU.S. CentersConclusionsIn conclusionPatientsMonthsInfarctionPossible targetsCareDoes Health Status Differ between Men And Women in Early Recovery after Myocardial Infarction
Garavalia LS, Decker C, Reid KJ, Lichtman JH, Parashar S, Vaccarino V, Krumholz HM, Spertus JA. Does Health Status Differ between Men And Women in Early Recovery after Myocardial Infarction. Journal Of Women's Health 2007, 16: 93-101. PMID: 17324100, DOI: 10.1089/jwh.2006.m073.Peer-Reviewed Original ResearchConceptsMyocardial infarctionHealth statusNon-ST segment elevation myocardial infarctionRisk-adjusted multivariable modelsSegment elevation myocardial infarctionChronic lung diseaseElevation myocardial infarctionWorse health statusPoor physical functioningQuality of lifeResidual anginaCoronary revascularizationHeart failureLung diseaseMI patientsPhysical functionMultivariable PoissonMultivariable modelPhysical functioningEarly recoveryGreater prevalenceInfarctionPatientsAdditional treatmentWomen
2006
Prevalence and Predictors of Angina Pectoris One Month After Myocardial Infarction
Spertus JA, Dawson J, Masoudi FA, Krumholz HM, Reid KJ, Peterson ED, Rumsfeld JS, Consortium C. Prevalence and Predictors of Angina Pectoris One Month After Myocardial Infarction. The American Journal Of Cardiology 2006, 98: 282-288. PMID: 16860010, DOI: 10.1016/j.amjcard.2006.01.099.Peer-Reviewed Original ResearchConceptsAngina pectorisMyocardial infarctionCoronary artery bypass surgeryPrevious coronary artery bypassMultivariable logistic regression analysisPatient's myocardial infarctionCoronary artery bypassSeattle Angina QuestionnaireArtery bypass surgeryLogistic regression analysisQuality of lifeIndex admissionAngina QuestionnaireArtery bypassIndex hospitalizationBypass surgeryYounger patientsTreatable symptomsTreatment characteristicsPatientsOne monthAdditional treatmentMonthsInfarctionRegression analysis
2004
Keeping the Patient in View
Curtis JP, Krumholz HM. Keeping the Patient in View. Circulation 2004, 110: 3746-3748. PMID: 15611387, DOI: 10.1161/01.cir.0000150389.35936.4d.Commentaries, Editorials and Letters
1999
Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial
Weintraub W, Culler S, Kosinski A, Becker E, Mahoney E, Burnette J, Spertus J, Feeny D, Cohen D, Krumholz H, Ellis S, Demopoulos L, Robertson D, Boccuzzi S, Barr E, Cannon C. Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial. The American Journal Of Cardiology 1999, 83: 317-322. PMID: 10072215, DOI: 10.1016/s0002-9149(98)00860-1.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsHealth Utilities IndexLife yearsHealth-related qualityCost-effectiveness methodsNon-Q-wave myocardial infarctionUtility indexCost-effectiveness analysisDetermine CostImpact of invasiveEconomic formsUB92 formulationHealth care costsUnstable anginaRelative value scaleMedicare conversion factorMyocardial infarctionMedicare fee scheduleDepartmental costsEconomicsExpensive formFee scheduleTACTICS-TIMI 18Care costsOutcomes of patients