2020
Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults
Mszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults. Stroke 2020, 51: 3552-3561. PMID: 33100188, DOI: 10.1161/strokeaha.120.031137.Peer-Reviewed Original ResearchMeSH KeywordsAdultAwarenessBlack or African AmericanEducational StatusEmigrants and ImmigrantsEthnicityFemaleHealth Knowledge, Attitudes, PracticeHispanic or LatinoHumansIncomeInsurance, HealthMaleMedically UninsuredStrokeUnited StatesWhite PeopleConceptsNational Health Interview SurveyCommon stroke symptomsStroke symptomsHealth Interview SurveyYoung adultsUS young adultsSymptom awarenessFocused public health interventionsInterview SurveyStroke symptom awarenessHigh-risk characteristicsPublic health interventionsArms/legsCertain sociodemographic subgroupsLow education levelStroke incidenceSevere headacheSingle symptomStudy populationTimely diagnosisHigher oddsStroke rateHispanic ethnicityGeneral populationSociodemographic determinants
2019
Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States
Mahajan S, Valero-Elizondo J, Khera R, Desai NR, Blankstein R, Blaha MJ, Virani SS, Kash BA, Zoghbi WA, Krumholz HM, Nasir K. Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States. JAMA Network Open 2019, 2: e1917885. PMID: 31851350, PMCID: PMC6991230, DOI: 10.1001/jamanetworkopen.2019.17885.Peer-Reviewed Original ResearchMeSH KeywordsAdultAwarenessCross-Sectional StudiesEmergency TreatmentEthnicityFemaleHealth Knowledge, Attitudes, PracticeHealth SurveysHealthcare DisparitiesHumansMyocardial InfarctionSocioeconomic FactorsUnited StatesConceptsMyocardial infarction symptomsShortness of breathMyocardial infarctionInfarction symptomsLow education levelEmergency medical servicesChest painSociodemographic subgroupsNational Health Interview SurveyEmergency cardiac careCross-sectional studyMedical servicesHealth Interview SurveyPublic health initiativesEducation levelLow-income subgroupsPrompt recognitionBack painCommon symptomsMale sexCardiac careHigher oddsHispanic ethnicityMAIN OUTCOMEHigh riskPrevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project
Mahajan S, Zhang D, He S, Lu Y, Gupta A, Spatz ES, Lu J, Huang C, Herrin J, Liu S, Yang J, Wu C, Cui J, Zhang Q, Li X, Nasir K, Zheng X, Krumholz HM, Li J, Dong Z, Jiang B, Zhang Y, Liu Y, Meng Y, Xi Y, Tian Y, Fu Y, Liu T, Yan S, Jin L, Wang J, Xu X, Xing X, Zhang L, Fang X, Xu Y, Xu C, Fan L, Qi M, Qi J, Li J, Liu Q, Feng Y, Wang J, Wen H, Xu J, He J, Jiang C, Yang C, Yu Y, Tashi Z, Hu Z, Zhang J, Li X, Ma S, Ma Y, Huang Y, Zhang Y, Shen J. Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project. Journal Of The American Heart Association 2019, 8: e012954. PMID: 31566101, PMCID: PMC6806046, DOI: 10.1161/jaha.119.012954.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntihypertensive AgentsBlood PressureChinaDiastoleFemaleHealth Knowledge, Attitudes, PracticeHumansHypertensionMaleMiddle AgedPractice Patterns, Physicians'PrevalenceSelf ReportTreatment OutcomeConceptsMillion Persons ProjectPrior cardiovascular eventsBody mass indexAntihypertensive medicationsDiastolic hypertensionCardiovascular eventsDiabetes mellitusMass indexIsolated diastolic hypertensionDiastolic blood pressureSelf-reported diagnosisTreatment of peoplePersons ProjectBlood pressureTreatment patternsHypertensionLeast collegeHigher likelihoodMellitusMedicationsPrevalenceTreatmentDiagnosisSubstantial numberCurrent useEffect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease
Zheng X, Spatz ES, Bai X, Huo X, Ding Q, Horak P, Wu X, Guan W, Chow CK, Yan X, Sun Y, Wang X, Zhang H, Liu J, Li J, Li X, Spertus JA, Masoudi FA, Krumholz HM. Effect of Text Messaging on Risk Factor Management in Patients With Coronary Heart Disease. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005616. PMID: 30998400, DOI: 10.1161/circoutcomes.119.005616.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsian PeopleBlood PressureChinaCoronary DiseaseCulturally Competent CareFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedPatient Education as TopicRisk AssessmentRisk FactorsSecondary PreventionSingle-Blind MethodTelemedicineText MessagingTime FactorsTreatment OutcomeConceptsCoronary heart diseaseSystolic blood pressureBody mass indexBlood pressureHeart diseaseSecondary preventionIntervention groupPhysical activityEnd pointSmoking statusMass indexControl groupPrimary end pointRisk factor controlSecondary end pointsRisk factor managementLDL-C levelsDisease-specific knowledgeMobile phone textMobile health technologyUsual careDiabetes mellitusMedication adherenceRisk factorsFactor management
2018
Comparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States
Lu Y, Wang P, Zhou T, Lu J, Spatz ES, Nasir K, Jiang L, Krumholz HM. Comparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States. Journal Of The American Heart Association 2018, 7: e007462. PMID: 29374046, PMCID: PMC5850247, DOI: 10.1161/jaha.117.007462.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntihypertensive AgentsAttitude of Health PersonnelBlood GlucoseBlood PressureBody Mass IndexCardiovascular DiseasesChinaDiabetes MellitusDyslipidemiasFemaleHealth Knowledge, Attitudes, PracticeHealth Status DisparitiesHumansHypertensionHypolipidemic AgentsLipidsLongitudinal StudiesMaleMiddle AgedNutrition SurveysObesityPractice Patterns, Physicians'PrevalencePrognosisRisk AssessmentRisk FactorsTime FactorsUnited StatesWaist CircumferenceConceptsHigher stroke prevalenceCardiovascular risk factorsHigh-sensitivity C-reactive proteinBody mass indexC-reactive proteinRisk factorsBlood pressureWaist circumferenceMass indexStroke prevalenceCardiovascular risk factor profileHigher mean blood pressureControl of hypertensionMean blood pressureBlood pressure levelsRisk factor profileComparison of prevalenceRepresentative population sampleLower ratesDyslipidemia awarenessSevere hypertensionHemoglobin A1cHypertension treatmentControl ratePlasma glucose
2017
Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project)
Lu J, Lu Y, Wang X, Li X, Linderman GC, Wu C, Cheng X, Mu L, Zhang H, Liu J, Su M, Zhao H, Spatz ES, Spertus JA, Masoudi FA, Krumholz HM, Jiang L. Prevalence, awareness, treatment, and control of hypertension in China: data from 1·7 million adults in a population-based screening study (China PEACE Million Persons Project). The Lancet 2017, 390: 2549-2558. PMID: 29102084, DOI: 10.1016/s0140-6736(17)32478-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAntihypertensive AgentsChinaFemaleHealth Knowledge, Attitudes, PracticeHumansHypertensionMaleMass ScreeningMiddle AgedPrevalenceSex FactorsConceptsControl of hypertensionBlood pressureAntihypertensive medicationsCardiac Events Million Persons ProjectSelf-reported antihypertensive medication usePopulation-based screening studyPopulation-based screening projectMillion Persons ProjectPrescribed antihypertensive medicationsPrevious cardiovascular eventsAntihypertensive medication useDiastolic blood pressureSystolic blood pressureManagement of hypertensionCalcium channel blockersProportion of participantsSelf-reported diagnosisCommunity-dwelling adultsSex-standardised ratesCardiovascular eventsHypertensive adultsMedication classesHypertension awarenessHypertension prevalenceClinical factors
2016
Gender differences in physical activity following acute myocardial infarction in adults: A prospective, observational study
Minges KE, Strait KM, Owen N, Dunstan DW, Camhi SM, Lichtman J, Geda M, Dreyer RP, Bueno H, Beltrame JF, Curtis JP, Krumholz HM. Gender differences in physical activity following acute myocardial infarction in adults: A prospective, observational study. European Journal Of Preventive Cardiology 2016, 24: 192-203. PMID: 27885060, DOI: 10.1177/2047487316679905.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAustraliaCardiac RehabilitationChi-Square DistributionExerciseExercise TherapyFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedMyocardial InfarctionOdds RatioPatient ComplianceProspective StudiesRisk FactorsSex FactorsSpainTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsAcute myocardial infarctionPost-acute myocardial infarctionMyocardial infarctionPhysical activityRegular physical activity participationYoung AMI Patients (VIRGO) studyPhysical activity recommendationsAmerican Heart AssociationPhysical activity trajectoriesNon-white raceMyocardial infarction recoveryPhysical activity participationGender differencesHospital dischargeHeart AssociationLifestyle behaviorsActivity recommendationsObservational studyInfarctionAustralian hospitalsTargeted interventionsOne monthPatientsTime pointsLonger duration
2015
Symptom Recognition and Healthcare Experiences of Young Women With Acute Myocardial Infarction
Lichtman JH, Leifheit-Limson EC, Watanabe E, Allen NB, Garavalia B, Garavalia LS, Spertus JA, Krumholz HM, Curry LA. Symptom Recognition and Healthcare Experiences of Young Women With Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2015, 8: s31-s38. PMID: 25714826, PMCID: PMC4801001, DOI: 10.1161/circoutcomes.114.001612.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsConflict, PsychologicalFemaleHealth Knowledge, Attitudes, PracticeHealth Status DisparitiesHealthcare DisparitiesHospitalizationHumansInterviews as TopicMiddle AgedMyocardial InfarctionPatient Acceptance of Health CarePreventive Health ServicesQualitative ResearchRecognition, PsychologyRisk AssessmentRisk FactorsSex FactorsTime FactorsTime-to-TreatmentConceptsAcute myocardial infarctionCare-seeking behaviorAcute careMyocardial infarctionProdromal symptomsHeart diseaseSymptom recognitionAcute myocardial infarction symptomsAcute myocardial infarction mortalityHealthcare systemMyocardial infarction symptomsPreventive health careCare-seeking experiencesMyocardial infarction mortalityAcute medical therapyPreventive health behaviorsCardiovascular riskMedical therapyPrompt recognitionPreventive carePrimary careInfarction symptomsAged menMortality riskHealth behaviors
2014
Predictors of clinical trial data sharing: exploratory analysis of a cross-sectional survey
Rathi VK, Strait KM, Gross CP, Hrynaszkiewicz I, Joffe S, Krumholz HM, Dzara K, Ross JS. Predictors of clinical trial data sharing: exploratory analysis of a cross-sectional survey. Trials 2014, 15: 384. PMID: 25277128, PMCID: PMC4192345, DOI: 10.1186/1745-6215-15-384.Peer-Reviewed Original ResearchMeSH KeywordsAccess to InformationAgedAttitude of Health PersonnelChi-Square DistributionClinical Trials as TopicCooperative BehaviorCross-Sectional StudiesDatabases, FactualFemaleHealth Knowledge, Attitudes, PracticeHumansInformation DisseminationInternetMaleMiddle AgedPerceptionRegistriesResearch PersonnelSurveys and QuestionnairesConceptsTrial funding sourceExact testMain outcome measuresFisher's exact testCross-sectional surveyChi-square testClinical trialsTrial characteristicsOutcome measuresGeneral medical journalsClinical trialistsWeb-based surveyTrialistsExploratory analysisBackgroundA numberStatistical significanceSignificant differencesExternal investigatorsClinical trial data sharingTrialsMedical journalsPharmaceutical companiesFunding sourcesIndustry fundingPotential respondents
2013
“I'm Not Just a Heart, I'm a Whole Person Here”: A Qualitative Study to Improve Sexual Outcomes in Women With Myocardial Infarction
Abramsohn EM, Decker C, Garavalia B, Garavalia L, Gosch K, Krumholz HM, Spertus JA, Lindau ST. “I'm Not Just a Heart, I'm a Whole Person Here”: A Qualitative Study to Improve Sexual Outcomes in Women With Myocardial Infarction. Journal Of The American Heart Association 2013, 2: e000199. PMID: 23885024, PMCID: PMC3828784, DOI: 10.1161/jaha.113.000199.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCounselingFearFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMaleMiddle AgedMotivationMyocardial InfarctionPatient Care TeamPhysician-Patient RelationsQualitative ResearchQuality of LifeRegistriesRisk FactorsSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalSexual PartnersTelephoneTime FactorsConceptsAcute myocardial infarctionMyocardial infarctionFemale sexual functionSexual functionSexual outcomesSexual activityAcute Myocardial Infarction Patients' Health Status (TRIUMPH) registryMost womenPost-MI outcomesLong-term female partnerQualitative telephone interviewsTreating cardiologistCare teamRehabilitation periodSafe resumptionHeart attackSexual concernsTelephone interviewsInfarctionSexual problemsKnowledge of recoveryTranslational researchWomenPartner's fearFemale partners
2012
A Note to My Younger Colleagues. . .Be Brave
Krumholz HM. A Note to My Younger Colleagues. . .Be Brave. Circulation Cardiovascular Quality And Outcomes 2012, 5: 245-246. PMID: 22592750, DOI: 10.1161/circoutcomes.112.966473.Peer-Reviewed Original Research
2005
Knowledge of Cholesterol Levels and Targets in Patients With Coronary Artery Disease
Cheng S, Lichtman JH, Amatruda JM, Smith GL, Mattera JA, Roumanis SA, Krumholz HM. Knowledge of Cholesterol Levels and Targets in Patients With Coronary Artery Disease. Preventive Cardiology 2005, 8: 11-17. PMID: 15722689, DOI: 10.1111/j.1520-037x.2005.3939.x.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseHigh-density lipoproteinLow-density lipoproteinCholesterol targetsArtery diseaseCholesterol levelsMultiple cardiac risk factorsCardiac risk factorsTotal cholesterol levelsTotal cholesterol valuesRisk factorsCardiovascular diseaseCholesterol valuesPrevious historyPatientsLipoproteinDiseaseCollege educationWomenNonwhitesEducation effortsNational targetsTargetCholesterol
2004
Clinical trial of an educational intervention to achieve recommended cholesterol levels in patients with coronary artery disease
Lichtman JH, Amatruda J, Yaari S, Cheng S, Smith GL, Mattera JA, Roumanis SA, Wang Y, Radford MJ, Krumholz HM. Clinical trial of an educational intervention to achieve recommended cholesterol levels in patients with coronary artery disease. American Heart Journal 2004, 147: 522-528. PMID: 14999204, DOI: 10.1016/j.ahj.2003.06.003.Peer-Reviewed Original ResearchMeSH KeywordsAgedCholesterol, LDLCoronary DiseaseFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedOutcome Assessment, Health CarePatient Education as TopicPractice Guidelines as TopicRisk FactorsConceptsLDL cholesterol target levelsCholesterol target levelsProportion of patientsCoronary artery diseaseUsual care groupArtery diseaseLevels 1 yearCholesterol managementCare groupEducational interventionPatient knowledgeLow-density lipoprotein cholesterol (LDL-C) target levelsTarget levelCholesterol knowledgeUsual careClinical characteristicsSecondary outcomesPrimary outcomeCholesterol levelsClinical trialsIntervention groupPatientsHospitalizationDiseaseIntervention