2018
The China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study design
Yu Y, Zhang H, Li X, Lu Y, Masoudi FA, Krumholz HM, Li J. The China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study design. BMJ Open 2018, 8: e020918. PMID: 29748344, PMCID: PMC5950642, DOI: 10.1136/bmjopen-2017-020918.Peer-Reviewed Original ResearchMeSH KeywordsChinaHeart FailureHospitalizationHumansObservational Studies as TopicPatient-Centered CareQuality ImprovementResearch DesignRetrospective StudiesTreatment OutcomeConceptsHeart failureChina PatientEthics CommitteeRetrospective cohort studyHeart Failure StudyCardiovascular disease prevalenceEthics committee approvalQuality of careHospital outcomesCohort studyPatient characteristicsLeading causeMedical recordsCardiovascular diseaseCase ascertainmentTreatment outcomesCurrent burdenCommittee approvalData abstractionDiagnostic testingPatient recordsCentral Ethics CommitteeLocal approvalPatientsStudy design
2016
Statins evidence: when answers also raise questions
Krumholz HM. Statins evidence: when answers also raise questions. The BMJ 2016, 354: i4963. PMID: 27628589, DOI: 10.1136/bmj.i4963.Peer-Reviewed Original ResearchPolypharmacy in the Aging Patient: A Review of Glycemic Control in Older Adults With Type 2 Diabetes
Lipska KJ, Krumholz H, Soones T, Lee SJ. Polypharmacy in the Aging Patient: A Review of Glycemic Control in Older Adults With Type 2 Diabetes. JAMA 2016, 315: 1034-1045. PMID: 26954412, PMCID: PMC4823136, DOI: 10.1001/jama.2016.0299.BooksConceptsRandomized clinical trialsIntensive glycemic controlGlycemic controlClinical trialsOlder adultsMicrovascular outcomesTreatment burdenPatient preferencesMost RCTsLarge randomized clinical trialsType 2 diabetes mellitusMajor macrovascular eventsStandard glycemic controlOptimal glycemic controlLower treatment burdenSurrogate end pointsHigh-quality evidenceType 2 diabetesLikelihood of benefitMajority of adultsGlycemic treatmentMacrovascular eventsDiabetes mellitusPatient factorsAging Patient
2015
The predicament of comparative effectiveness research using observational data.
Curtis JP, Krumholz HM. The predicament of comparative effectiveness research using observational data. Annals Of Internal Medicine 2015, 163: 799-800. PMID: 26501410, PMCID: PMC6467208, DOI: 10.7326/m15-2490.Commentaries, Editorials and LettersAcute Coronary SyndromeComparative Effectiveness ResearchCoronary AngiographyHumansObservational Studies as Topic