2020
Where Skilled Nursing Facility Residents Get Acute Care: Is the Emergency Department the Medical Home?
Venkatesh AK, Gettel CJ, Mei H, Chou SC, Rothenberg C, Liu SL, D’Onofrio G, Lin Z, Krumholz HM. Where Skilled Nursing Facility Residents Get Acute Care: Is the Emergency Department the Medical Home? Journal Of Applied Gerontology 2020, 40: 828-836. PMID: 32842827, PMCID: PMC7904961, DOI: 10.1177/0733464820950125.Peer-Reviewed Original ResearchMeSH KeywordsAgedCross-Sectional StudiesEmergency Service, HospitalHumansMedicarePatient DischargePatient-Centered CareSkilled Nursing FacilitiesUnited StatesConceptsAcute care visitsCare visitsEmergency departmentMedicare beneficiariesSNF staySNF servicesSkilled nursing facility residentsNursing facility residentsSkilled nursing facility servicesAcute care capabilitiesCross-sectional analysisNursing facility servicesHigher proportionAcute careMedical homeFacility residentsCare capabilitiesVisitsNumber of daysStayCareDepartmentFacility servicesBeneficiariesProportion
2019
Characterizing Patient‐Centered Postoperative Recovery After Adult Cardiac Surgery: A Systematic Review
Mori M, Angraal S, Chaudhry SI, Suter LG, Geirsson A, Wallach JD, Krumholz HM. Characterizing Patient‐Centered Postoperative Recovery After Adult Cardiac Surgery: A Systematic Review. Journal Of The American Heart Association 2019, 8: e013546. PMID: 31617435, PMCID: PMC6898802, DOI: 10.1161/jaha.119.013546.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiac Surgical ProceduresEnhanced Recovery After SurgeryHumansPatient Reported Outcome MeasuresPatient-Centered CareConceptsPatient-reported outcome measuresPostoperative patient-reported outcome measuresAdult cardiac surgeryPostoperative recoveryOutcome measuresCardiac surgerySystematic reviewCoronary artery bypass graftSingle-center settingArtery bypass graftQuality of evidenceWeb of ScienceNociceptive symptomsDiversity of patientsLess comorbidityAdult patientsBypass graftPhysical functionPostacute careElective casesInclusion criteriaDaily livingPatientsStudy participantsCognitive functionThe China Patient-centred Evaluative Assessment of Cardiac Events (PEACE) prospective heart failure study design
Huang X, Yu Y, Li X, Masoudi FA, Spertus JA, Yan X, Krumholz HM, Jiang L, Li J. The China Patient-centred Evaluative Assessment of Cardiac Events (PEACE) prospective heart failure study design. BMJ Open 2019, 9: e025144. PMID: 30782925, PMCID: PMC6377534, DOI: 10.1136/bmjopen-2018-025144.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesHeart failureChina PatientMedical historyCardiac Events Prospective Heart Failure StudyDisease-specific health statusEthics CommitteeCardiovascular risk factorsProspective cohort studyMin walk testHeart Failure StudyPatient's medical historyLocal ethics committeeQuality of careCollection of bloodHF hospitalisationHospitalisation eventsHospital outcomesCohort studyPatient demographicsTransthoracic echocardiogramWalk testHospital treatmentMedical recordsRisk factors
2018
Admission diagnoses among patients with heart failure: Variation by ACO performance on a measure of risk-standardized acute admission rates
Benchetrit L, Zimmerman C, Bao H, Dharmarajan K, Altaf F, Herrin J, Lin Z, Krumholz HM, Drye EE, Lipska KJ, Spatz ES. Admission diagnoses among patients with heart failure: Variation by ACO performance on a measure of risk-standardized acute admission rates. American Heart Journal 2018, 207: 19-26. PMID: 30404047, DOI: 10.1016/j.ahj.2018.09.006.Peer-Reviewed Original ResearchMeSH KeywordsAccountable Care OrganizationsAgedAlgorithmsAnalysis of VarianceCardiovascular DiseasesComorbidityFemaleHeart FailureHospitalizationHumansInternational Classification of DiseasesMaleMedicare Part AMedicare Part BPatient AdmissionPatient DischargePatient-Centered CareSex DistributionTime FactorsUnited StatesConceptsHeart failureAccountable care organizationsMean admission rateAdmission ratesAdmission typeAcute admission ratesNoncardiovascular conditionsAdmission diagnosisCause admission ratesMedicare Shared Savings Program Accountable Care OrganizationsRate of hospitalizationPrincipal discharge diagnosisProportion of admissionsType of admissionNoncardiovascular causesHF admissionsHF patientsPerson yearsDischarge diagnosisPatient populationPatientsAdmissionKey quality metricDiagnosisSubstantial proportionThe China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study design
Yu Y, Zhang H, Li X, Lu Y, Masoudi FA, Krumholz HM, Li J. The China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study design. BMJ Open 2018, 8: e020918. PMID: 29748344, PMCID: PMC5950642, DOI: 10.1136/bmjopen-2017-020918.Peer-Reviewed Original ResearchConceptsHeart failureChina PatientEthics CommitteeRetrospective cohort studyHeart Failure StudyCardiovascular disease prevalenceEthics committee approvalQuality of careHospital outcomesCohort studyPatient characteristicsLeading causeMedical recordsCardiovascular diseaseCase ascertainmentTreatment outcomesCurrent burdenCommittee approvalData abstractionDiagnostic testingPatient recordsCentral Ethics CommitteeLocal approvalPatientsStudy design
2017
Priorities for Cardiovascular Outcomes Research
Khazanie P, Krumholz HM, Kiefe CI, Kressin NR, Wells B, Wang TY, Peterson ED. Priorities for Cardiovascular Outcomes Research. Circulation Cardiovascular Quality And Outcomes 2017, 10: e001967. PMID: 28710296, PMCID: PMC7811766, DOI: 10.1161/circoutcomes.115.001967.Peer-Reviewed Original ResearchCardiologyCost-Benefit AnalysisDelivery of Health CareHealth Care CostsHealth Services ResearchHumansInterdisciplinary CommunicationNational Heart, Lung, and Blood Institute (U.S.)Organizational ObjectivesOutcome Assessment, Health CarePatient-Centered CarePublic-Private Sector PartnershipsStakeholder ParticipationTranslational Research, BiomedicalUnited StatesPatient–Provider Communication and Health Outcomes Among Individuals With Atherosclerotic Cardiovascular Disease in the United States
Okunrintemi V, Spatz ES, Di Capua P, Salami JA, Valero-Elizondo J, Warraich H, Virani SS, Blaha MJ, Blankstein R, Butt AA, Borden WB, Dharmarajan K, Ting H, Krumholz HM, Nasir K. Patient–Provider Communication and Health Outcomes Among Individuals With Atherosclerotic Cardiovascular Disease in the United States. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003635. PMID: 28373270, DOI: 10.1161/circoutcomes.117.003635.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAspirinAtherosclerosisCommunicationEmergency Service, HospitalFemaleHealth Care CostsHealth Care SurveysHealth ExpendituresHealth StatusHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLength of StayMaleMental HealthMiddle AgedOdds RatioPatient Reported Outcome MeasuresPatient-Centered CarePhysician-Patient RelationsPlatelet Aggregation InhibitorsQuality Indicators, Health CareRisk FactorsUnited StatesYoung AdultConceptsAtherosclerotic cardiovascular diseasePatient-provider communicationHealthcare resource utilizationPatient-reported outcomesCardiovascular diseaseHealth Plans SurveyMedical Expenditure Panel Survey cohortHigher annual healthcare expendituresRepresentative US adult populationHealthcare expendituresAtherosclerotic cardiovascular disease (ASCVD) patientsConsumer AssessmentEmergency room visitsEvidence-based therapiesAnnual healthcare expendituresCardiovascular disease patientsUS adult populationPlans SurveyMental health statusPatient-centered careOutcomes of interestASA useHospital stayRoom visitsPoor outcome
2016
The New Era of Informed Consent: Getting to a Reasonable-Patient Standard Through Shared Decision Making
Spatz ES, Krumholz HM, Moulton BW. The New Era of Informed Consent: Getting to a Reasonable-Patient Standard Through Shared Decision Making. JAMA 2016, 315: 2063. PMID: 27099970, PMCID: PMC5459384, DOI: 10.1001/jama.2016.3070.Peer-Reviewed Original ResearchMeSH KeywordsConsent FormsDecision MakingDisclosureHumansInformed ConsentPatient Education as TopicPatient ParticipationPatient-Centered CareUnited NationsUnited StatesConceptsInformed consentThe china patient‐centered evaluative assessment of cardiac events (PEACE) prospective study of percutaneous coronary intervention: Study design
Du X, Pi Y, Dreyer RP, Li J, Li X, Downing NS, Li L, Feng F, Zhan L, Zhang H, Guan W, Xu X, Li S, Lin Z, Masoudi FA, Spertus JA, Krumholz HM, Jiang L, Group F. The china patient‐centered evaluative assessment of cardiac events (PEACE) prospective study of percutaneous coronary intervention: Study design. Catheterization And Cardiovascular Interventions 2016, 88: e212-e221. PMID: 26945565, PMCID: PMC5215582, DOI: 10.1002/ccd.26461.Peer-Reviewed Original ResearchMeSH KeywordsChinaClinical ProtocolsCoronary AngiographyHealth StatusHealthcare DisparitiesHumansMedication AdherenceMyocardial InfarctionPatient Reported Outcome MeasuresPatient-Centered CarePercutaneous Coronary InterventionPredictive Value of TestsProspective StudiesResearch DesignRisk AssessmentRisk FactorsSecondary PreventionTime FactorsTreatment OutcomeConceptsPercutaneous coronary interventionPatient-reported outcomesCardiovascular risk factor controlRisk factor controlProspective studyHealth statusMedical historyLong-term clinical outcomesLong-term patient outcomesHospital-level factorsIndependent core laboratoryNationwide prospective studyLong-term outcomesPatient's medical historyHospital outcomesCoronary interventionPatient demographicsSecondary preventionConsecutive patientsMedical chartsPCI indicationPrimary outcomeClinical outcomesClinical presentationHealthcare utilizationThe China Patient-Centred Evaluative Assessment of Cardiac Events (China PEACE)-Prospective Study of 3-Vessel Disease: rationale and design
Rao C, Bongiovanni T, Li X, Gao H, Zhang H, Li J, Zhao Y, Yuan X, Hua K, Hu S, Krumholz HM, Jiang L, Zheng Z. The China Patient-Centred Evaluative Assessment of Cardiac Events (China PEACE)-Prospective Study of 3-Vessel Disease: rationale and design. BMJ Open 2016, 6: e009743. PMID: 26880670, PMCID: PMC4762131, DOI: 10.1136/bmjopen-2015-009743.Peer-Reviewed Original ResearchConceptsComplex coronary artery diseaseCoronary artery diseaseArtery diseaseLarge cardiovascular centresCardiac eventsProspective studyCardiovascular CenterTreatment strategiesCoronary revascularisation proceduresSYNTAX score calculationThree-vessel diseaseElective coronary angiographyMedical record abstractionPatient-reported outcomesAppropriateness of treatmentQuality improvement initiativesQuality of lifeEligible patientsRevascularisation proceduresAdverse eventsGuideline adherenceHospital factorsProspective cohortSecondary preventionCoronary angiographyChina Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design
Li J, Dreyer RP, Li X, Du X, Downing NS, Li L, Zhang HB, Feng F, Guan WC, Xu X, Li SX, Lin ZQ, Masoudi FA, Spertus JA, Krumholz HM, Jiang LX, Group T. China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design. Chinese Medical Journal 2016, 129: 72-80. PMID: 26712436, PMCID: PMC4797546, DOI: 10.4103/0366-6999.172596.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultChinaFemaleHospitalizationHumansMaleMyocardial InfarctionPatient-Centered CareProspective StudiesQuality of LifeRisk FactorsYoung AdultConceptsPatient-reported outcomesAcute myocardial infarctionChina PatientMedical historyMyocardial infarctionPatient experienceLong-term adverse eventsRisk factor controlConsecutive AMI patientsAMI studyPatient's medical historyQuality of lifeNational Coordinating CentreQuality improvement activitiesHospital outcomesCardiac eventsPatient demographicsAdverse eventsMedical chartsHealthcare utilizationAMI patientsMedication adherenceProspective studyHospitalization eventsRisk factorsProtocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Million Persons Project pilot
Lu J, Xuan S, Downing NS, Wu C, Li L, Krumholz HM, Jiang L. Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Million Persons Project pilot. BMJ Open 2016, 6: e010200. PMID: 26729395, PMCID: PMC4716208, DOI: 10.1136/bmjopen-2015-010200.Peer-Reviewed Original ResearchConceptsHigh-risk subjectsCardiovascular diseaseBlood pressureMedical historyFurther health assessmentsLipid blood testsMillion Persons ProjectPotential lifestyle changesReturn clinic visitsPopulation-based assessmentCommunity-dwelling residentsHealth-related behaviorsCollection of bloodBaseline characteristicsClinic visitsBlood testsLeading causeSurvival statusLifestyle changesHigh riskUrine analysisHealth statusAnthropometric variablesTelephone interviewsCentral Ethics Committee
2015
Do Non-Clinical Factors Improve Prediction of Readmission Risk? Results From the Tele-HF Study
Krumholz HM, Chaudhry SI, Spertus JA, Mattera JA, Hodshon B, Herrin J. Do Non-Clinical Factors Improve Prediction of Readmission Risk? Results From the Tele-HF Study. JACC Heart Failure 2015, 4: 12-20. PMID: 26656140, PMCID: PMC5459404, DOI: 10.1016/j.jchf.2015.07.017.Peer-Reviewed Original ResearchConceptsReadmission ratesPatient-reported informationHeart failureHealth statusReadmission riskC-statisticRisk scorePsychosocial variablesMedical record abstractionWeeks of dischargeReadmission risk modelNon-clinical factorsCandidate risk factorsReadmission risk predictionRecord abstractionClinical variablesPatient interviewsMedical recordsRisk factorsPatientsPsychosocial informationPsychosocial characteristicsTelephone interviewsRisk predictionScoresNational Quality Assessment Evaluating Spironolactone Use During Hospitalization for Acute Myocardial Infarction (AMI) in China: China Patient‐centered Evaluation Assessment of Cardiac Events (PEACE)‐Retrospective AMI Study, 2001, 2006, and 2011
Guan W, Murugiah K, Downing N, Li J, Wang Q, Ross JS, Desai NR, Masoudi FA, Spertus JA, Li X, Krumholz HM, Jiang L, Group T. National Quality Assessment Evaluating Spironolactone Use During Hospitalization for Acute Myocardial Infarction (AMI) in China: China Patient‐centered Evaluation Assessment of Cardiac Events (PEACE)‐Retrospective AMI Study, 2001, 2006, and 2011. Journal Of The American Heart Association 2015, 4: e001718. PMID: 26071031, PMCID: PMC4599529, DOI: 10.1161/jaha.114.001718.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failureMyocardial infarctionUse of spironolactoneNational practice patternsProportion of patientsAssessment of eligibilitySpironolactone useAldosterone antagonistsSystolic dysfunctionCardiac eventsAMI patientsChina PatientPatient eligibilityPatient groupUnknown indicationPractice patternsIdeal patientPatientsSpironolactoneEligibilityAppropriate useInfarctionDiabetesNational quality assessmentNational assessment of early β-blocker therapy in patients with acute myocardial infarction in China, 2001-2011: The China Patient-centered Evaluative Assessment of Cardiac Events (PEACE)–Retrospective AMI Study
Zhang H, Masoudi FA, Li J, Wang Q, Li X, Spertus JA, Ross JS, Desai NR, Krumholz HM, Jiang L, Group C. National assessment of early β-blocker therapy in patients with acute myocardial infarction in China, 2001-2011: The China Patient-centered Evaluative Assessment of Cardiac Events (PEACE)–Retrospective AMI Study. American Heart Journal 2015, 170: 506-515.e1. PMID: 26385034, PMCID: PMC5459420, DOI: 10.1016/j.ahj.2015.05.012.Peer-Reviewed Original ResearchConceptsΒ-blocker therapyAcute myocardial infarctionΒ-blocker useCardiogenic shockRisk factorsAbsolute contraindicationMyocardial infarctionEarly β-blocker useLower systolic blood pressureHours of admissionMedical record reviewSystolic blood pressureClinical practice guidelinesLower heart rateQuality of careChest discomfortCardiac eventsBlood pressureRecord reviewChina PatientIdeal patientPractice guidelinesHeart rateHigh riskPatterns of use
2014
Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention
Li J, Dharmarajan K, Li X, Lin Z, Normand SL, Krumholz HM, Jiang L, Group F. Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention. BMJ Open 2014, 4: e004595. PMID: 24607563, PMCID: PMC3948460, DOI: 10.1136/bmjopen-2013-004595.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary catheterisationCoronary interventionPatient characteristicsRetrospective studyCardiovascular diseaseComplications of treatmentCost of hospitalisationMedical record abstractionPatterns of careDiagnostic testing patternsTwo-stage clusterHospital outcomesRecord abstractionChinese healthcare systemStudy protocolCase ascertainmentImproved careCatheterisationProcedural treatmentsHospitalCentral Ethics CommitteeChinese hospitalsPatientsChina National Center
2012
Seeing through the eyes of patients: the Patient-Centered Outcomes Research Institute Funding Announcements.
Krumholz HM, Selby JV. Seeing through the eyes of patients: the Patient-Centered Outcomes Research Institute Funding Announcements. Annals Of Internal Medicine 2012, 157: 446-7. PMID: 22847044, DOI: 10.7326/0003-4819-157-6-201209180-00519.Peer-Reviewed Original Research
2011
Cardiac Care for Older Adults Time for a New Paradigm
Forman DE, Rich MW, Alexander KP, Zieman S, Maurer MS, Najjar SS, Cleveland JC, Krumholz HM, Wenger NK. Cardiac Care for Older Adults Time for a New Paradigm. Journal Of The American College Of Cardiology 2011, 57: 1801-1810. PMID: 21527153, PMCID: PMC4942282, DOI: 10.1016/j.jacc.2011.02.014.Peer-Reviewed Original Research
2010
Informed Consent to Promote Patient-Centered Care
Krumholz HM. Informed Consent to Promote Patient-Centered Care. JAMA 2010, 303: 1190-1191. PMID: 20332406, DOI: 10.1001/jama.2010.309.Peer-Reviewed Original Research
2008
Outcomes Research
Krumholz HM. Outcomes Research. Circulation 2008, 118: 309-318. PMID: 18625906, DOI: 10.1161/circulationaha.107.690917.Peer-Reviewed Original Research