2012
Trends in Survival after In-Hospital Cardiac Arrest
Girotra S, Nallamothu BK, Spertus JA, Li Y, Krumholz HM, Chan PS. Trends in Survival after In-Hospital Cardiac Arrest. New England Journal Of Medicine 2012, 367: 1912-1920. PMID: 23150959, PMCID: PMC3517894, DOI: 10.1056/nejmoa1109148.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestPulseless electrical activityCardiac arrestRisk-adjusted ratesNeurologic disabilityIn-Hospital Cardiac ArrestAcute resuscitation survivalGuidelines-Resuscitation registrySignificant neurologic disabilityQuality improvement registryPulseless ventricular tachycardiaElectrical activityInitial rhythmNeurologic outcomePostresuscitation careAcute resuscitationNeurologic functionSurvival improvementPostresuscitation survivalResuscitation careVentricular tachycardiaRhythm groupVentricular fibrillationMultivariable regressionSurvivalA Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest
Chan PS, Spertus JA, Krumholz HM, Berg RA, Li Y, Sasson C, Nallamothu BK, Investigators F. A Validated Prediction Tool for Initial Survivors of In-Hospital Cardiac Arrest. JAMA Internal Medicine 2012, 172: 947-953. PMID: 22641228, PMCID: PMC3517176, DOI: 10.1001/archinternmed.2012.2050.Peer-Reviewed Original ResearchConceptsFavorable neurological survivalHospital cardiac arrestNeurological survivalCardiac arrestNeurological statusDerivation cohortValidation cohortInitial cardiac arrest rhythmIn-Hospital Cardiac ArrestBaseline neurological statusFavorable neurological statusGuidelines-Resuscitation registryCardiac arrest rhythmSevere neurological deficitsPulseless ventricular tachycardiaMultivariate logistic regressionSimple prediction toolRenal insufficiencyArrest rhythmNeurological deficitsHepatic insufficiencyMechanical ventilationMalignant diseaseVentricular tachycardiaInitial survivors
2009
Racial Differences in Survival After In-Hospital Cardiac Arrest
Chan PS, Nichol G, Krumholz HM, Spertus JA, Jones PG, Peterson ED, Rathore SS, Nallamothu BK, Investigators F. Racial Differences in Survival After In-Hospital Cardiac Arrest. JAMA 2009, 302: 1195-1201. PMID: 19755698, PMCID: PMC2795316, DOI: 10.1001/jama.2009.1340.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestBlack patientsWhite patientsSuccessful resuscitationPostresuscitation survivalRacial differencesHospital sitesIn-Hospital Cardiac ArrestLower ratesPulseless ventricular tachycardiaRate of survivalCohort studyHospital dischargePatient characteristicsClinical factorsImmediate resuscitationPostresuscitation periodNational registryVentricular tachycardiaHospital CenterVentricular fibrillationCardiopulmonary resuscitationAdditional adjustmentPatients
2008
Delayed Time to Defibrillation after In-Hospital Cardiac Arrest
S. C, M. K, Graham N, K. N, Investigators T. Delayed Time to Defibrillation after In-Hospital Cardiac Arrest. New England Journal Of Medicine 2008, 358: 9-17. PMID: 18172170, DOI: 10.1056/nejmoa0706467.Peer-Reviewed Original ResearchMeSH KeywordsAgedComorbidityElectric CountershockFemaleHeart ArrestHeart FailureHospital Bed CapacityHospital MortalityHospitalizationHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionRetrospective StudiesSurvival AnalysisTachycardia, VentricularTime FactorsVentricular FibrillationConceptsHospital cardiac arrestCardiac arrestHospital dischargeIn-Hospital Cardiac ArrestOverall median timePulseless ventricular tachycardiaMultivariable logistic regressionLower ratesMedian timeVentricular arrhythmiasBlack raceHospital characteristicsNational registryVentricular tachycardiaCardiopulmonary resuscitationExpert guidelinesVentricular fibrillationHospital unitsLogistic regressionPatientsDefibrillationSurvivalArrestHospitalMinutes of delay
1997
Determinants of Appropriate Use of Angiotensin-Converting Enzyme Inhibitors After Acute Myocardial Infarction in Persons ≥65 Years of Age
Krumholz H, Vaccarino V, Ellerbeck E, Kiefe C, Hennen J, Kresowik T, Gold J, Jencks S, Radford M. Determinants of Appropriate Use of Angiotensin-Converting Enzyme Inhibitors After Acute Myocardial Infarction in Persons ≥65 Years of Age. The American Journal Of Cardiology 1997, 79: 581-586. PMID: 9068512, DOI: 10.1016/s0002-9149(96)00819-3.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlabamaAngiotensin-Converting Enzyme InhibitorsConnecticutContraindicationsControlled Clinical Trials as TopicDecision MakingDiabetes ComplicationsDiureticsDrug PrescriptionsDrug UtilizationFemaleFollow-Up StudiesHeart FailureHospitalizationHumansIowaMaleMedicaidMultivariate AnalysisMyocardial InfarctionPatient DischargeRetrospective StudiesStroke VolumeTachycardia, VentricularUnited StatesVentricular Function, LeftWisconsinConceptsAcute myocardial infarctionACE inhibitorsMyocardial infarctionDischarge medicationsVentricular functionEnzyme inhibitorsLeft ventricular ejection fractionAngiotensin-converting enzyme inhibitorAngiotensin converting enzyme (ACE) inhibitorsVentricular Enlargement (SAVE) trialCongestive heart failureVentricular ejection fractionYears of ageEligible patientsPatient characteristicsAppropriate patientsDiabetes mellitusEjection fractionHeart failureLoop diureticsMultivariable analysisVentricular tachycardiaIdeal patientObservational studyPatients