2020
Assessment of Prevalence, Awareness, and Characteristics of Isolated Systolic Hypertension Among Younger and Middle-Aged Adults in China
Mahajan S, Feng F, Hu S, Lu Y, Gupta A, Murugiah K, Gao Y, Lu J, Liu J, Zheng X, Spatz ES, Zhang H, Krumholz HM, Li J. Assessment of Prevalence, Awareness, and Characteristics of Isolated Systolic Hypertension Among Younger and Middle-Aged Adults in China. JAMA Network Open 2020, 3: e209743. PMID: 33289843, PMCID: PMC7724558, DOI: 10.1001/jamanetworkopen.2020.9743.Peer-Reviewed Original ResearchConceptsMiddle-aged adultsSystolic hypertensionCardiac Events Million Persons ProjectOlder individualsIsolated systolic hypertensionManagement of ISHMillion Persons ProjectPrevalence of ISHPrevious cardiovascular eventsSystolic blood pressureTypes of hypertensionAssessment of prevalenceCross-sectional studyHypertension subtypesCardiovascular eventsBlood pressureChina PatientMean ageHypertensionMAIN OUTCOMEAwareness ratePrevalenceAged adultsYoung adultsAdults
2005
Systolic Hypertension in Older Persons: Complexities in Clinical Decision Making
Foody JM, Chaudhry SI, Krumholz HM. Systolic Hypertension in Older Persons: Complexities in Clinical Decision Making. The American Journal Of Geriatric Cardiology 2005, 14: 325-330. PMID: 16276131, DOI: 10.1111/j.1076-7460.2005.04537.x.BooksConceptsOlder personsSystolic hypertensionHypertension treatment decisionsJoint National CommitteeBlood pressure controlHigh blood pressureEvidence-based careHealth care providersFinal management planHealth care decisionsOlder patientsBlood pressurePatient preferencesSeventh ReportTreatment preferencesTreatment decisionsIndividual patientsIndividualized riskTreatment goalsCare providersClinical decisionPressure controlMost health care decisionsCare decisionsPatients
2004
Systolic Hypertension in Older Persons
Chaudhry SI, Krumholz HM, Foody JM. Systolic Hypertension in Older Persons. JAMA 2004, 292: 1074-1080. PMID: 15339901, DOI: 10.1001/jama.292.9.1074.BooksConceptsSystolic blood pressureSystolic hypertensionBlood pressureOlder personsOlder patientsClinical trialsBaseline systolic blood pressureTolerance of therapyJoint National CommitteeFirst-line therapyDiastolic blood pressureHigh blood pressureCalcium channel blockersRandomized clinical trialsTreatment of patientsEnglish-language literatureLarge-scale trialsSearch terms hypertensionAntihypertensive therapyCardiovascular riskThiazide diureticsDATA EXTRACTIONPatient preferencesSeventh ReportTerm hypertension
2001
Pulse pressure and risk of cardiovascular events in the systolic hypertension in the elderly program
Vaccarino V, Berger A, Abramson J, Black H, Setaro J, Davey J, Krumholz H. Pulse pressure and risk of cardiovascular events in the systolic hypertension in the elderly program. The American Journal Of Cardiology 2001, 88: 980-986. PMID: 11703993, DOI: 10.1016/s0002-9149(01)01974-9.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseRisk of HFSystolic hypertensionRisk of strokeHeart failurePulse pressureCardiovascular eventsBlood pressureElderly ProgramRisk factorsTreatment groupsIncidence of CHDPlacebo-controlled clinical trialOlder adultsIsolated systolic hypertensionDiastolic blood pressureSystolic blood pressureElevated pulse pressureInfluence of treatmentCardiovascular outcomesPlacebo groupSystolic pressureDiastolic pressureHeart diseaseClinical trialsDepression and Risk of Heart Failure Among Older Persons With Isolated Systolic Hypertension
Abramson J, Berger A, Krumholz HM, Vaccarino V. Depression and Risk of Heart Failure Among Older Persons With Isolated Systolic Hypertension. JAMA Internal Medicine 2001, 161: 1725-1730. PMID: 11485505, DOI: 10.1001/archinte.161.14.1725.Peer-Reviewed Original ResearchConceptsHeart failureSystolic hypertensionMyocardial infarctionDepressed personsOlder personsCox proportional hazards regressionEpidemiological Studies Depression ScaleIsolated systolic hypertensionIncident heart failureCoronary heart diseaseProportional hazards regressionBlood pressureElectrocardiographic abnormalitiesHazards regressionElderly ProgramCholesterol levelsHeart diseaseRisk factorsNondepressed personsDepression ScaleAdditional adjustmentElevated riskHigh riskTreatment groupsHypertension
1993
Sex differences in cardiac adaptation to isolated systolic hypertension
Krumholz H, Larson M, Levy D. Sex differences in cardiac adaptation to isolated systolic hypertension. The American Journal Of Cardiology 1993, 72: 310-313. PMID: 8342510, DOI: 10.1016/0002-9149(93)90678-6.Peer-Reviewed Original ResearchConceptsSystolic hypertensionLV massBlood pressureLV hypertrophyApparent cardiovascular diseaseDiastolic blood pressureBody mass indexLeft ventricular massLV wall thicknessM-mode echocardiographyM-mode echocardiogramsFramingham Offspring StudyBlood glucose levelsFramingham Heart StudyAntihypertensive medicationsDiastolic hypertensionNormotensive subjectsConcentric hypertrophyLV dilationMass indexIndex examinationChamber enlargementVentricular massCardiac adaptationCardiovascular disease