2024
Cause-Specific Mortality Rates Among the US Black Population
Arun A, Caraballo C, Sawano M, Lu Y, Khera R, Yancy C, Krumholz H. Cause-Specific Mortality Rates Among the US Black Population. JAMA Network Open 2024, 7: e2436402. PMID: 39348122, PMCID: PMC11443349, DOI: 10.1001/jamanetworkopen.2024.36402.Peer-Reviewed Original Research
2019
Do pregnant women living in higher well-being populations in the USA experience lower risk of preterm delivery? A cross-sectional study
Riley C, Roy B, Herrin J, Spatz E, Silvestri MT, Arora A, Kell KP, Rula EY, Krumholz HM. Do pregnant women living in higher well-being populations in the USA experience lower risk of preterm delivery? A cross-sectional study. BMJ Open 2019, 9: e024143. PMID: 31048427, PMCID: PMC6501974, DOI: 10.1136/bmjopen-2018-024143.Peer-Reviewed Original ResearchConceptsPreterm birthCross-sectional studyIndividual risk factorsPreterm deliveryRisk factorsPregnant womenLower riskMaternal risk factorsPrimary outcome measurePrimary independent variableGestational ageMaternal riskOutcome measuresUS birthsHealth StatisticsBirth dataBeing IndexWomenBirthGallup-Sharecare WellLower ratesQuintileRiskDeliveryPopulation
2018
Accurate estimation of cardiovascular risk in a non-diabetic adult: detecting and correcting the error in the reported Framingham Risk Score for the Systolic Blood Pressure Intervention Trial population
Warner F, Dhruva SS, Ross JS, Dey P, Murugiah K, Krumholz HM. Accurate estimation of cardiovascular risk in a non-diabetic adult: detecting and correcting the error in the reported Framingham Risk Score for the Systolic Blood Pressure Intervention Trial population. BMJ Open 2018, 8: e021685. PMID: 30037874, PMCID: PMC6059296, DOI: 10.1136/bmjopen-2018-021685.Peer-Reviewed Original ResearchConceptsSystolic Blood Pressure Intervention TrialFramingham risk scoreCardiovascular riskRisk scoreStudy populationStudy participantsNon-diabetic adultsTotal study populationHigh-risk populationClinical trial dataClinical trial sitesTrial populationIntervention trialsRisk populationsNew England JournalIndependent investigatorsTrial dataSecondary analysisSPRINT trialSPRINT dataTrialsRiskScoresParticipantsPopulation
2017
The primary health-care system in China
Li X, Lu J, Hu S, Cheng K, De Maeseneer J, Meng Q, Mossialos E, Xu DR, Yip W, Zhang H, Krumholz HM, Jiang L, Hu S. The primary health-care system in China. The Lancet 2017, 390: 2584-2594. PMID: 29231837, DOI: 10.1016/s0140-6736(17)33109-4.Peer-Reviewed Original ResearchConceptsPrimary health care systemHealth care systemChronic non-communicable diseasesEvidence-based performance indicatorsNon-communicable diseasesEveryday clinical practiceQuality of careHealth information technology systemsRisk factorsClinical practiceCare deliveryVillage doctorsHealth care reformInadequate educationCost savingsWorld populationPopulationPrevalenceDisease
2014
Impact of the ENHANCE Trial on the use of ezetimibe in the United States and Canada
Lu L, Krumholz HM, Tu JV, Ross JS, Ko DT, Jackevicius CA. Impact of the ENHANCE Trial on the use of ezetimibe in the United States and Canada. American Heart Journal 2014, 167: 683-689. PMID: 24766978, PMCID: PMC4215424, DOI: 10.1016/j.ahj.2014.01.014.Peer-Reviewed Original ResearchConceptsUse of ezetimibeENHANCE trialEzetimibe useProgression of atherosclerosisMain outcome measuresAtherosclerosis regression trialsMonthly numberOutcome measuresRegression trialsEzetimibeIMS HealthCommon evidence baseEvidence baseTrialsUnited StatesUtilization patternsFurther investigationDifferent utilization patternsPopulationDifferent patternsUse trendsAtherosclerosisSimvastatinProgression
2011
US Cardiologist Workforce From 1995 To 2007: Modest Growth, Lasting Geographic Maldistribution Especially In Rural Areas
Aneja S, Ross JS, Wang Y, Matsumoto M, Rodgers GP, Bernheim SM, Rathore SS, Krumholz HM. US Cardiologist Workforce From 1995 To 2007: Modest Growth, Lasting Geographic Maldistribution Especially In Rural Areas. Health Affairs 2011, 30: 2301-2309. PMID: 22147857, PMCID: PMC3332098, DOI: 10.1377/hlthaff.2011.0255.Peer-Reviewed Original ResearchConceptsPrimary care physiciansCare physiciansGeographic maldistributionChronic cardiovascular diseaseHospital referral regionsUse of telemedicineCardiology workforceNumber of cardiologistsTotal physician workforceCardiovascular diseaseCardiovascular careReferral regionsElderly populationUS populationTotal physiciansCardiologistsPhysiciansAge sixtyPhysician workforceDisadvantaged areasPercentRural areasPopulationDiseaseVariety of strategiesUse of Fibrates in the United States and Canada
Jackevicius CA, Tu JV, Ross JS, Ko DT, Carreon D, Krumholz HM. Use of Fibrates in the United States and Canada. JAMA 2011, 305: 1217-1224. PMID: 21427374, PMCID: PMC3332101, DOI: 10.1001/jama.2011.353.Peer-Reviewed Original ResearchMeSH KeywordsCanadaCardiovascular DiseasesCohort StudiesCosts and Cost AnalysisDiabetes Mellitus, Type 2Drug CostsDrugs, GenericFenofibrateFibric AcidsHealth ExpendituresHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsMedical AuditPractice Patterns, Physicians'PrescriptionsUnited StatesConceptsUse of fibratesRole of fibratesObservational cohort studyIMS Health dataFenofibrate useCardiovascular riskCohort studyDiabetes (ACCORD) trialClinical benefitFibratesMonthsPrescriptionUnited StatesPatientsNegative resultsFenofibrateHealth dataCurrent useGeneric formulationPopulationStatinsTherapyTrialsUse of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study
Dorfman AL, Fazel R, Einstein AJ, Applegate KE, Krumholz HM, Wang Y, Christodoulou E, Chen J, Sanchez R, Nallamothu BK. Use of Medical Imaging Procedures With Ionizing Radiation in Children: A Population-Based Study. JAMA Pediatrics 2011, 165: 458-464. PMID: 21199972, PMCID: PMC3686496, DOI: 10.1001/archpediatrics.2010.270.Peer-Reviewed Original ResearchConceptsDiagnostic imaging proceduresTomographic scanImaging proceduresRetrospective cohort analysisPopulation-based ratesPediatric populationPlain radiographyCohort analysisHigh dosesMedical diagnostic imaging proceduresStudy periodAppropriate useChildrenHigh rateMedical imaging proceduresScansFrequent useHealth care marketUS health care marketYearsPatientsInfantsPopulationCare marketUnitedHealthcare
2006
Driving Times and Distances to Hospitals With Percutaneous Coronary Intervention in the United States
Nallamothu BK, Bates ER, Wang Y, Bradley EH, Krumholz HM. Driving Times and Distances to Hospitals With Percutaneous Coronary Intervention in the United States. Circulation 2006, 113: 1189-1195. PMID: 16520425, DOI: 10.1161/circulationaha.105.596346.Peer-Reviewed Original ResearchConceptsNon-PCI hospitalsPercutaneous coronary interventionST-elevation myocardial infarctionPCI hospitalsAdult populationCoronary interventionPrehospital triage protocolsAdults 18 yearsCross-sectional studyAmerican Hospital Association Annual SurveyHospital-level dataMedian timeMyocardial infarctionDirect referralTriage protocolHospitalTimely accessPatientsUnited StatesMinutesCensus tract-level dataInterventionTract-level dataTransport timePopulation
2002
The Burden of Chronic Congestive Heart Failure in Older Persons: Magnitude and Implications for Policy and Research
Masoudi FA, Havranek EP, Krumholz HM. The Burden of Chronic Congestive Heart Failure in Older Persons: Magnitude and Implications for Policy and Research. Heart Failure Reviews 2002, 7: 9-16. PMID: 11790919, DOI: 10.1023/a:1013793621248.Peer-Reviewed Original ResearchConceptsHeart failureOlder populationChronic congestive heart failureOlder personsPoor long-term survivalMore hospital admissionsCongestive heart failureLong-term survivalHospital admissionHigh riskFailureSingle conditionPopulationPersonsHospitalizationAdmissionDearth of researchYearsDiagnosisMonths