2022
Effectiveness of a clinical decision support system for hypertension management in primary care: study protocol for a pragmatic cluster-randomized controlled trial
Song J, Wang X, Wang B, Gao Y, Liu J, Zhang H, Li X, Li J, Wang JG, Cai J, Herrin J, Armitage J, Krumholz HM, Zheng X. Effectiveness of a clinical decision support system for hypertension management in primary care: study protocol for a pragmatic cluster-randomized controlled trial. Trials 2022, 23: 412. PMID: 35578345, PMCID: PMC9109449, DOI: 10.1186/s13063-022-06374-x.Peer-Reviewed Original ResearchConceptsHypertension managementPrimary carePrimary outcomeDual antihypertensive therapyHypertension Treatment TrialBlood pressure managementGuideline-based treatmentPrimary care sitesCluster-randomized trialUnit of randomizationGuideline-based decision support systemClinical decision support systemAntihypertensive regimensAntihypertensive treatmentUsual careGuideline adherenceBlood pressureMiddle-income countriesTreatment trialsManagement visitsStudy protocolCare sitesPatientsTrialsPressure management
2017
Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research
Engelgau MM, Peprah E, Sampson UKA, Mishoe H, Benjamin IJ, Douglas PS, Hochman JS, Ridker PM, Brandes N, Checkley W, El-Saharty S, Ezzati M, Hennis A, Jiang L, Krumholz HM, Lamourelle G, Makani J, Narayan KMV, Ohene-Frempong K, Straus SE, Stuckler D, Chambers DA, Belis D, Bennett GC, Boyington JE, Creazzo TL, de Jesus JM, Krishnamurti C, Lowden MR, Punturieri A, Shero ST, Young NS, Zou S, Mensah GA. Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research. Global Heart 2017, 12: 341-348. PMID: 27452772, DOI: 10.1016/j.gheart.2016.03.640.Peer-Reviewed Original ResearchConceptsNational HeartDisease burdenNoncommunicable disease burdenHealth delivery modelsGlobal health researchMiddle-income countriesBlood InstituteGlobal health disparitiesThink Tank meetingHealth disparitiesEffective interventionsCompelling scientific questionsLungTank meetingHealth researchSustainable interventionsHeartThree-quartersDelivery modelInterventionBurdenImplementation strategiesResearch capacityMajor themesLater stages
2015
Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study
Zhan L, Masoudi FA, Li X, Hu S, Venkatesh AK, Spertus JA, Lin Z, Desai NR, Li J, Krumholz HM, Jiang L, . Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study. PLOS ONE 2015, 10: e0122237. PMID: 25893247, PMCID: PMC4404305, DOI: 10.1371/journal.pone.0122237.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac biomarker testingProportion of hospitalsBiomarker testingChinese hospitalsDiagnosis of AMIChina PEACE-Retrospective AMI StudyRate of useMiddle-income countriesMyocardial infarctionPractice compliesHigh-income countriesAMI admissionsBiomarker testsUrban hospitalBiomarker use
2012
Building Hospital Management Capacity to Improve Patient Flow for Cardiac Catheterization at a Cardiovascular Hospital in Egypt
Wong R, Hathi S, Linnander EL, Banna A, Maraghi M, Din R, Ahmed A, Hafez AR, Allam AA, Krumholz HM, Bradley EH. Building Hospital Management Capacity to Improve Patient Flow for Cardiac Catheterization at a Cardiovascular Hospital in Egypt. The Joint Commission Journal On Quality And Patient Safety 2012, 38: 147-153. PMID: 22533126, PMCID: PMC3427659, DOI: 10.1016/s1553-7250(12)38019-7.Peer-Reviewed Original ResearchConceptsCardiac catheterizationPre-post intervention studyPercentage of patientsPatient flowPre-intervention periodNational Heart InstituteCatheterization laboratory proceduresResource-limited settingsSubset of proceduresTotal patientsConsecutive patientsMiddle-income countriesCardiovascular HospitalPostintervention periodHeart InstituteHospital careHigh-income countriesQI interventionsPatientsCatheterization proceduresIntervention studiesCatheterizationPatient crowdingWard unitSignificant reduction
2011
Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004
Cherlin EJ, Allam AA, Linnander EL, Wong R, El-Toukhy E, Sipsma H, Krumholz HM, Curry LA, Bradley EH. Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004. BMC Health Services Research 2011, 11: 282. PMID: 22014078, PMCID: PMC3216250, DOI: 10.1186/1472-6963-11-282.Peer-Reviewed Original ResearchConceptsHealth unitsMiddle-income countriesHealth facilitiesHealth Survey websiteService Provision Assessment surveyMinority of facilitiesQuality improvement initiativesRural health unitsUrban health unitsCross-sectional analysisHealth care deliveryMinistry of HealthHealth reformMeasure DemographicFinal sampleGeneral service hospitalsMore rural partsService hospitalsChild healthStandard frequency analysisCare deliveryFacility characteristicsHealth careStatistical significanceImprovement initiatives
2010
Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities
Safavi K, Linnander EL, Allam AA, Bradley EH, Krumholz HM. Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities. Asia Pacific Journal Of Public Health 2010, 22: 90s-95s. PMID: 20566539, DOI: 10.1177/1010539510373017.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCardiovascular diseaseCoronary syndromeHealth systemClinical Outcomes RegistryEvidence-based careCause of deathResource limited settingsResource-limited settingsWorld health systemsQuality improvement activitiesMiddle-income countriesOutcomes RegistryHigh-quality treatmentBlame-free cultureClinical registryRegistrySyndromeImprovement activitiesHospitalDiseaseSetting