Insulin-Sensitizing Antihyperglycemic Drugs and Mortality After Acute Myocardial Infarction
Inzucchi SE, Masoudi FA, Wang Y, Kosiborod M, Foody JM, Setaro JF, Havranek EP, Krumholz HM. Insulin-Sensitizing Antihyperglycemic Drugs and Mortality After Acute Myocardial Infarction. Diabetes Care 2005, 28: 1680-1689. PMID: 15983320, DOI: 10.2337/diacare.28.7.1680.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYear of dischargeHeart failureAntihyperglycemic agentsMyocardial infarctionHigh riskDiabetic patientsInsulin sensitizersMultivariable Cox proportional hazards modelsCox proportional hazards modelBorderline higher riskOlder diabetic patientsRetrospective cohort studyHeart failure readmissionInsulin-sensitizing drugsProportional hazards modelFirst rehospitalizationCause readmissionCohort studySecondary outcomesDischarge prescriptionsPrimary outcomeMultivariable analysisAntihyperglycemic drugsIndependent associationThiazolidinediones, Metformin, and Outcomes in Older Patients With Diabetes and Heart Failure
Masoudi FA, Inzucchi SE, Wang Y, Havranek EP, Foody JM, Krumholz HM. Thiazolidinediones, Metformin, and Outcomes in Older Patients With Diabetes and Heart Failure. Circulation 2005, 111: 583-590. PMID: 15699279, DOI: 10.1161/01.cir.0000154542.13412.b1.Peer-Reviewed Original ResearchConceptsHeart failureInsulin-sensitizing drugsOlder patientsLower riskCox proportional hazards modelAntidiabetic drug prescriptionRetrospective cohort studyPrincipal discharge diagnosisClustering of patientsProportional hazards modelCohort studySecondary outcomesPrimary outcomeMetformin treatmentRandomized trialsThiazolidinedione treatmentDischarge diagnosisInsulin sensitizersAdverse outcomesDrug prescriptionsMultivariable modelObservational studyHospital variablesThiazolidinedione classHigh risk