2018
Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies
Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Bolton T, Paige E, Paul DS, Sweeting M, Burgess S, Bell S, Astle W, Stevens D, Koulman A, Selmer RM, Verschuren WMM, Sato S, Njølstad I, Woodward M, Salomaa V, Nordestgaard BG, Yeap BB, Fletcher A, Melander O, Kuller LH, Balkau B, Marmot M, Koenig W, Casiglia E, Cooper C, Arndt V, Franco OH, Wennberg P, Gallacher J, de la Cámara AG, Völzke H, Dahm CC, Dale CE, Bergmann MM, Crespo CJ, van der Schouw YT, Kaaks R, Simons LA, Lagiou P, Schoufour JD, Boer JMA, Key TJ, Rodriguez B, Moreno-Iribas C, Davidson KW, Taylor JO, Sacerdote C, Wallace RB, Quiros JR, Tumino R, Blazer DG, Linneberg A, Daimon M, Panico S, Howard B, Skeie G, Strandberg T, Weiderpass E, Nietert PJ, Psaty BM, Kromhout D, Salamanca-Fernandez E, Kiechl S, Krumholz HM, Grioni S, Palli D, Huerta JM, Price J, Sundström J, Arriola L, Arima H, Travis RC, Panagiotakos DB, Karakatsani A, Trichopoulou A, Kühn T, Grobbee DE, Barrett-Connor E, van Schoor N, Boeing H, Overvad K, Kauhanen J, Wareham N, Langenberg C, Forouhi N, Wennberg M, Després JP, Cushman M, Cooper JA, Rodriguez CJ, Sakurai M, Shaw JE, Knuiman M, Voortman T, Meisinger C, Tjønneland A, Brenner H, Palmieri L, Dallongeville J, Brunner EJ, Assmann G, Trevisan M, Gillum RF, Ford I, Sattar N, Lazo M, Thompson SG, Ferrari P, Leon DA, Smith GD, Peto R, Jackson R, Banks E, Di Angelantonio E, Danesh J, Group E, Wood A, Kaptoge S, Butterworth A, Willeit P, Warnakula S, Bolton T, Paige E, Paul D, Sweeting M, Burgess S, Bell S, Astle W, Stevens D, Koulman A, Selmer R, Verschuren M, Sato S, Njølstad I, Woodward M, Veikko S, Nordestgaard B, Yeap B, Flecther A, Melander O, Kuller L, Balkau B, Marmot M, Koenig W, Casiglia E, Cooper C, Arndt V, Franco O, Wennberg P, Gallacher J, de la Cámara A, Völzke H, Dahm C, Dale C, Bergmann M, Crespo C, van der Schouw Y, Kaaks R, Simons L, Lagiou P, Schoufour J, Boer J, Key T, Rodriguez B, Moreno-Iribas C, Davidson K, Taylor J, Sacerdote C, Wallace R, Quiros J, Rimm E, Tumino R, Blazer D, Linneberg A, Daimon M, Panico S, Howard B, Skeie G, Salomaa V, Strandberg T, Weiderpass E, Nietert P, Psaty B, Kromhout D, Salamanca-Fernandez E, Kiechl S, Krumholz H, Grioni S, Palli D, Huerta J, Price J, Sundström J, Arriola L, Arima H, Travis R, Panagiotakos D, Karakatsani A, Trichopoulou A, Kühn T, Grobbee D, Barrett-Connor E, van Schoor N, Boeing H, Overvad K, Kauhanen J, Wareham N, Langenberg C, Forouhi N, Wennberg M, Després J, Cushman M, Cooper J, Rodriguez C, Sakurai M, Shaw J, Knuiman M, Voortman T, Meisinger C, Tjønneland A, Brenner H, Palmieri L, Dallongeville J, Brunner E, Assmann G, Trevisan M, Gillumn R, Ford I, Sattar N, Lazo M, Thompson S, Ferrari P, Leon D, Smith G, Peto R, Jackson R, Banks E, Di Angelantonio E, Danesh J. Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies. The Lancet 2018, 391: 1513-1523. PMID: 29676281, PMCID: PMC5899998, DOI: 10.1016/s0140-6736(18)30134-x.Peer-Reviewed Original ResearchConceptsIndividual participant dataCardiovascular disease subtypesCause mortalityCurrent drinkersCardiovascular diseaseHazard ratioAlcohol consumptionMyocardial infarctionLower riskProspective studyHigh-income countriesDisease subtypesIncident cardiovascular disease eventsFatal aortic aneurysmsMinimum mortality riskTotal cardiovascular diseasePrevious cardiovascular diseaseCardiovascular disease eventsHistory of diabetesDose-response associationUK Medical Research CouncilAge 40 yearsAlcohol consumption amountBritish Heart FoundationWeeks of alcohol
2015
Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study
Zhan L, Masoudi FA, Li X, Hu S, Venkatesh AK, Spertus JA, Lin Z, Desai NR, Li J, Krumholz HM, Jiang L, . Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study. PLOS ONE 2015, 10: e0122237. PMID: 25893247, PMCID: PMC4404305, DOI: 10.1371/journal.pone.0122237.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac biomarker testingProportion of hospitalsBiomarker testingChinese hospitalsDiagnosis of AMIChina PEACE-Retrospective AMI StudyRate of useMiddle-income countriesMyocardial infarctionPractice compliesHigh-income countriesAMI admissionsBiomarker testsUrban hospitalBiomarker use
2012
Building Hospital Management Capacity to Improve Patient Flow for Cardiac Catheterization at a Cardiovascular Hospital in Egypt
Wong R, Hathi S, Linnander EL, Banna A, Maraghi M, Din R, Ahmed A, Hafez AR, Allam AA, Krumholz HM, Bradley EH. Building Hospital Management Capacity to Improve Patient Flow for Cardiac Catheterization at a Cardiovascular Hospital in Egypt. The Joint Commission Journal On Quality And Patient Safety 2012, 38: 147-153. PMID: 22533126, PMCID: PMC3427659, DOI: 10.1016/s1553-7250(12)38019-7.Peer-Reviewed Original ResearchConceptsCardiac catheterizationPre-post intervention studyPercentage of patientsPatient flowPre-intervention periodNational Heart InstituteCatheterization laboratory proceduresResource-limited settingsSubset of proceduresTotal patientsConsecutive patientsMiddle-income countriesCardiovascular HospitalPostintervention periodHeart InstituteHospital careHigh-income countriesQI interventionsPatientsCatheterization proceduresIntervention studiesCatheterizationPatient crowdingWard unitSignificant reduction
2011
Gender Differences in Presentation, Management, and In-Hospital Outcomes for Patients with AMI in a Lower-Middle Income Country: Evidence from Egypt
Butala NM, Desai MM, Linnander EL, Wong YR, Mikhail DG, Ott LS, Spertus JA, Bradley EH, Aaty AA, Abdelfattah A, Gamal A, Kholeif H, Baz M, Allam AH, Krumholz HM. Gender Differences in Presentation, Management, and In-Hospital Outcomes for Patients with AMI in a Lower-Middle Income Country: Evidence from Egypt. PLOS ONE 2011, 6: e25904. PMID: 22022463, PMCID: PMC3192760, DOI: 10.1371/journal.pone.0025904.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHospital outcomesFemale patientsInitial presentationClinical managementDiagnosis of AMIIncome countriesIn-Hospital OutcomesOutcomes of patientsTime of presentationMultivariate logistic regressionGender differencesQuality of careLow-middle income countriesHospital mortalityHospital deathDiabetes mellitusHeart failureAtrial fibrillationHigher BMIMyocardial infarctionCardiovascular diseaseRegistry dataHigh-income countriesEgyptian hospitals